Hemp Bombs' Certified Cannabidiol Pain Gel formula has the potential to ease the pain caused by rheumatoid arthritis and osteoarthritis. An easy-to-apply topical solution, our CBD Pain Freeze has properties that can reduce arthritic pain and swelling. Beneficial for everyday use, our CBD Pain Rub is safe to use and can provide therapeutic potential for various symptoms caused by arthritis such as inflammation, stiffness, and joint damage.


We would never sacrifice quality by providing a synthetic CBD or CBD isolate blend. We use a whole plant extract that is rich in cannabinoids, terpenes, and other beneficial oils. The Hadassah Medical School at the Hebrew University of Jerusalem sought to compare the effectiveness of a completely purified CBD extract versus a full-spectrum extract of cannabis flowers containing large quantities of CBD. The conclusion of the study was that the whole plant extract, which contained a large percentage of CBD but also contained traces of the other cannabinoids, proved far more effective than CBD-only solutions in alleviating inflammation and pain sensation.

By the 1930s, marijuana was banned in 24 states. The newly minted Federal Bureau of Narcotics launched a campaign against the drug, and newspapers fueled hysteria with headlines like the 1933 Los Angeles Examiner's "Murder Weed Found Up and Down the Coast — Deadly Marihuana Dope Plant Ready for Harvest That Means Enslavement of California Children." By 1937, Congress passed the Marihuana Tax Act, which effectively banned marijuana except for a few medicinal purposes, according to "Smoke Signals: A Social History of Marijuana – Medical, Recreational and Legal" (Scribner, 2012).

As people age, they normally lose nerve cells in a region of the brain that is important for remembering events. Chronic exposure to THC may hasten the age-related loss of these nerve cells. In one study, researchers found that rats exposed to THC every day for eight months (about one-third of their life span) showed a loss of brain cells comparable to rats that were twice their age. It is not known whether a similar effect occurs in humans. Researchers are still learning about the many ways that marijuana could affect the brain.

In 2014, the Kentucky legislature revised the definition of marijuana under state law to create legal protection for patients who use a cannabidiol (CBD) medicine as part of an approved clinical trial or on the written order of “a physician practicing at a hospital or associated clinic affiliated with a Kentucky public university having a college or school of medicine.”


This is because California also taxes the crops before they are even sold. Other states such as Alaska and Colorado sit between 10%-20% per sale. In some cases, California can have taxes as high as 80% if you include some Federal Taxes. What this means is that the margin of profits are so small, that it almost becomes impossible to operate a legitimate cannabis business according to their rules.
Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.

Hemp oil is an oil extracted from the hemp plant. All plants in the Cannabis genus can produce the oil, but usually only industrial hemp is used to make hemp oil. Industrial hemp is a hemp varietal which has been cultivated specifically for industrial production, and it has a minimum of the psychoactive substances associated with the genus, most notably THC. Hemp oil is typically almost free of THC, and it has no psychoactive properties.

Update January 1st, 2018: State laws surrounding CBD are starting to make a grey area even greyer as states such as Indiana are currently seeking to make CBD imported from outside of the state, illegal for residents inside the state that qualify for CBD possession under current state laws. Alaska has made selling hemp based CBD against the law for local marijuana shops to sell, but other stores are still free to sell imported hemp oils. All CBD oils sold at local marijuana shops in Alaska currently, must be produced within the state, under the current state guidelines for marijuana production.
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.

Although hemp and marijuana are essentially different cultivars of the same plant – Cannabis sativa L – marijuana has been cultivated to concentrate high levels of THC (frequently as much as 18%), in the plant’s flowering tops, whereas hemp, which is primarily grown in Europe to make clothing, paper, biofuels, bioplastics, nutritional supplements, cosmetics, and foods, contains less than 0.3% THC.
Overall, researchers agree that while there isn’t conclusive data to support CBD oil as the preferred method of pain management, these types of products have a lot of potential. CBD products might be able to offer relief for many people who have chronic pain, all without causing intoxication and dependence. Oil versions of CBD may not be as effective as other forms, and more human studies are needed.

Been using product for a few days now ,I'm about one my 6th dose. I noticed today my hand from nerve damage has not dropped anything or felt numb,or even trembled. Even axienty has been managable. However I'm taking 250mgs.I boosted it up to 500mgs.3 or 4 times daily ,of 250mgs. It seems to have best effect atleast today.It's cold and rainy which,is better than snow ,is my most hightened pain days.Today 4/24/18. Has been a God send! 1 pain and axienty day free ...Makes me a believer! I stand by this products effectiveness. Hope my review helps another soul,that lives with same aliments.
^ Jump up to: a b c Devinsky, Orrin; Cilio, Maria Roberta; Cross, Helen; Fernandez-Ruiz, Javier; French, Jacqueline; Hill, Charlotte; Katz, Russell; Di Marzo, Vincenzo; Jutras-Aswad, Didier; Notcutt, William George; Martinez-Orgado, Jose; Robson, Philip J.; Rohrback, Brian G.; Thiele, Elizabeth; Whalley, Benjamin; Friedman, Daniel (22 May 2014). "Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders". Epilepsia. 55 (6): 791–802. doi:10.1111/epi.12631. PMC 4707667. PMID 24854329.
Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.
A 2008 study found, “that a controlled cannabis extract, containing multiple cannabinoids, in a defined ratio, and other non-cannabinoid fractions (terpenes and flavonoids) provided better antinociceptive efficacy than the single cannabinoid given alone…” This is why the use of full-spectrum CBD oil is more effective in treating pain than taking CBD isolate alone – you want the beneficial terpenes and flavonoids contained in the plant. 

Refined hempseed oil is clear and colorless, with little flavor and lacks natural vitamins and antioxidants. Refined hempseed oil is primarily used in body care products. Industrial hempseed oil is used in lubricants, paints, inks, fuel, and plastics. Hempseed oil is used in the production of soaps, shampoos and detergents. The oil has a 3:1 ratio of omega-6 to omega-3 essential fatty acids.[3] It may also be used as a feedstock for the large-scale production of biodiesel.[4]
Jackson Leyden had always been a healthy kid; he practiced taekwondo, and he played lacrosse and baseball. But in 2011, a few months after his eighth birthday, he began having seizures several times a day. Many were brief, a half-minute of staring into space, but he also had severe episodes in which he would collapse, sometimes injuring himself. Over the next two years, he was hospitalized about 50 times, and he missed much of fourth and fifth grade.

Refined hempseed oil is clear and colorless, with little flavor and lacks natural vitamins and antioxidants. Refined hempseed oil is primarily used in body care products. Industrial hempseed oil is used in lubricants, paints, inks, fuel, and plastics. Hempseed oil is used in the production of soaps, shampoos and detergents. The oil has a 3:1 ratio of omega-6 to omega-3 essential fatty acids.[3] It may also be used as a feedstock for the large-scale production of biodiesel.[4]


^ Gobbi, Gabriella; Atkin, Tobias; Zytynski, Tomasz; Wang, Shouao; Askari, Sorayya; Boruff, Jill; Ware, Mark; Marmorstein, Naomi; Cipriani, Andrea; Dendukuri, Nandini; Mayo, Nancy (13 February 2019). "Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood". JAMA Psychiatry. doi:10.1001/jamapsychiatry.2018.4500. Retrieved 13 February 2019.
So instead, go with an American company who has built up a good reputation of selling high-quality products. Every Day Optimal is by far one of the best in the business right now. They have amazing purification processes that take their quality to the next level. Furthermore, they only use medicinal hemp, which is the best grade possible! Their company has developed a unique structure which allows them to carry out quality checks at any given time. The CBD products they sell are also 100% legal to use.
In June 2014, the New York Assembly passed S7923, which creates legal protections for patients and caregivers and authorizes the state to license and regulate “registered organizations” to cultivate and sell medical cannabis to patients. Patients must obtain a registration identification card after getting written certification from their physician.
I was on a road trip and the pain in my knee and feet was terrible. I saw this at a gas station and bought it. within five minute my pain was gone and I was able to finish my road trip pain free. I stopped back at the gas station to buy 2 more of the little jars so I have one for my purse, my work bag and my husband has one also. I have used it every day for my RA in my feet and it has really helped. I am hoping combining it with an oral oil will get me off the tons of Ibuprofen I have been having to take every day. I am so excited.
This article will attempt to present information concerning cannabinoid mechanisms of analgesia, review randomized clinical trials (RCTs) of available and emerging cannabinoid agents, and address the many thorny issues that have arisen with clinical usage of herbal cannabis itself (“medical marijuana”). An effort will be made to place the issues in context and suggest rational approaches that may mitigate concerns and indicate how standardized pharmaceutical cannabinoids may offer a welcome addition to the pharmacotherapeutic armamentarium in chronic pain treatment.
Unlike other CBD oils, PureKana really does excel in CBD oil extractions due to their unique CO2 extraction process which provides a near 99% pure CBD oil. PureKana Natural CBD Oil is an unflavored, dietary and nutritional supplement for increased health and vitality. It is extremely effective in treating chronic pain, inflammation, swelling, anxiety and sleep disorders.
In 1972, the Dutch government divided drugs into more- and less-dangerous categories, with cannabis being in the lesser category. Accordingly, possession of 30 grams or less was made a misdemeanor.[213] Cannabis has been available for recreational use in coffee shops since 1976.[214] Cannabis products are only sold openly in certain local "coffeeshops" and possession of up to 5 grams for personal use is decriminalised, however: the police may still confiscate it, which often happens in car checks near the border. Other types of sales and transportation are not permitted, although the general approach toward cannabis was lenient even before official decriminalisation.[215][216][217]
According to the United Nations Office on Drugs and Crime (UNODC), "the amount of THC present in a cannabis sample is generally used as a measure of cannabis potency."[158] The three main forms of cannabis products are the flower, resin (hashish), and oil (hash oil). The UNODC states that cannabis often contains 5% THC content, resin "can contain up to 20% THC content", and that "Cannabis oil may contain more than 60% THC content."[158]
Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.

Dry mouth: As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth (or cottonmouth). This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation. In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth.

So. According to the Controlled Substance Act definition itself, certain parts of the cannabis plant are clearly illegal, while others fall into a grayer area. One of these – for the most part – is CBD extracted from the “legal” parts of the cannabis plant, and non-marijuana industrial hemp plants, which, as defined by Section 7606 of the Farm Bill are cannabis plants with less than 0.3 percent THC.


This cream is amazing. I have repurchased 16 more jars. I have customers coming back asking when I will get it back in stock. My experence has been to apply lightly on area of pain, once it has absorbed, reapply to same area. I have seem it work on sciatic nerve in customers back and leg, I have saw it work on lower back pain , shoulder pain and also heard raving reviews for skin issues from my customers. Will always keep in stock.
CBD Oil refers to CBD-infused products that contain CBD suspended in an oily base, such as vegetable glycerin, hemp seed oil, or another plant-derived oil. Sublingual oils are ideal because they allow for rapid absorption of CBD through the membrane under your tongue directly into your bloodstream. CBD Oils are available in both low and high doses, and droppers built into the cap make it easy to measure your proper dose. CBD Oils are the most popular kind of CBD product thanks to their ease of use and rapid effects.
I appreciate the Fast delivery and thorough packaging. Had my wife try this last night and she compared it to a different brand hemp product she has been using. She likes your product better, especially because it does not have an awful taste like the other product. it provided some pain relief for her RA and fibro but the initial dosage may not have been enough drops. She tried about 20 droplets and was able to sleep through the night.
For some, a sore muscle on your lower back may feel better after using a CBD patch. For others, a headache might respond well to a CBD tincture. Pain is a universal feeling, but we respond differently and our bodies react in different ways depending on our overall health. The variety of ways in which CBD is consumed allows customers to pick a method based on their specific condition and their personal preference. For example, someone with sensitive lungs who doesn’t like smoking may prefer treating their pain with CBD capsules. Someone who takes a lot of pills, in general, may enjoy the experience of vaporizing. CBD is a naturally occurring chemical compound found in the cannabis and hemp plants. It does not produce the difficult side effects that those on prescription opioids commonly experience.
People are turning to CBD oil to treat their pain more and more. Whether acute to chronic, pain can be located in different areas of the body and may be experienced at different intensities. This wide range of pain complaints among individual may call for different types of treatment that are more comprehensive than just swallowing a general prescription pill. The good news is that CBD can be applied topically or consumed orally. Furthermore, CBD can be taken sublingually, smoked, eaten, or even vaporized, depending on the product. In this way, CBD can treat pain very specifically rather than generally, because let’s face it, one size does not fit all.
Cannabis has mental and physical effects, such as creating a "high" or "stoned" feeling, a general change in perception, heightened mood, and an increase in appetite.[21][22] Onset of effects is within minutes when smoked, and about 30 to 60 minutes when cooked and eaten.[21][23] They last for between two and six hours.[23] Short-term side effects may include a decrease in short-term memory, dry mouth, impaired motor skills, red eyes, and feelings of paranoia or anxiety.[21][24][25] Long-term side effects may include addiction, decreased mental ability in those who started as teenagers, and behavioral problems in children whose mothers used cannabis during pregnancy.[21] There is a strong relation between cannabis use and the risk of psychosis,[26] though the cause-and-effect is debated.[27]
CBD is a 5-HT1A receptor agonist, which may also contribute to an anxiolytic effect.[155] This likely means the high concentrations of CBD found in Cannabis indica mitigate the anxiogenic effect of THC significantly.[155] The cannabis industry claims that sativa strains provide a more stimulating psychoactive high while indica strains are more sedating with a body high.[156] However this is disputed by researchers.[157]
The Gateway Hypothesis states that cannabis use increases the probability of trying "harder" drugs. The hypothesis has been hotly debated as it is regarded by some as the primary rationale for the United States prohibition on cannabis use.[260][261] A Pew Research Center poll found that political opposition to marijuana use was significantly associated with concerns about health effects and whether legalization would increase marijuana use by children.[262]
^ El-Alfy, Abir T.; Ivey, Kelly; Robinson, Keisha; Ahmed, Safwat; Radwan, Mohamed; Slade, Desmond; Khan, Ikhlas; Elsohly, Mahmoud; Ross, Samir (2010). "Antidepressant-like effect of Δ9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L". Pharmacology Biochemistry and Behavior. 95 (4): 573–82. doi:10.1016/j.pbb.2010.03.004. PMC 2866040. PMID 20332000.

Hemp is often mistaken for its cannabis cousin, marijuana, even though smoking an entire garbage bag of hemp would not produce an altered state of consciousness, as hemp contains low levels of THC. Confusion between hemp oil and marijuana oil has spiked recently, as states have passed medical marijuana laws that allow for the use of strains of marijuana that are low in THC and high in CBD. Consumers often confuse hemp oil with CBD oil because both are low in THC and contain CBD.

According to PeaceHealth, a website dedicated to providing information on an array of different supplements and medications, hemp oil can cause minor side effects in the digestive system. For example, the website suggests that hemp and hemp oil can soften the stools, often leading to diarrhea or abdominal cramping. Many times, excessive diarrhea can lead to increased weight loss or malabsorption. While further research is needed to substantiate these side effect claims, it is recommended that for individuals with a history of digestive disorders or irregular bowel movements to not take hemp oil supplements.

Cannabis is indigenous to Central Asia[191] and the Indian subcontinent,[192] and its use for fabric and rope dates back to the Neolithic age in China and Japan.[193][194] It is unclear when cannabis first became known for its psychoactive properties; some scholars suggest that the ancient Indian drug soma, mentioned in the Vedas, was cannabis, although this theory is disputed.[195]
CBD directly interacts with a number of proteins in the body and central nervous system, a few of which are components of the endogenous cannabinoid system. For instance, CBD binds to both the CB1 and CB2 cannabinoid receptors, but it binds in a way that sets off a reaction that is essentially the opposite of what THC does. CBD is an inverse agonist, while THC is an agonist at CB1. Simply put, CBD is not intoxicating; at the molecular level, it does the opposite of what THC does. Our bodies have several other receptor proteins that participate in the endogenous cannabinoid system (GPR3, GPR6, TRPV1 and TRPV2, for example). CBD binds to all of these, and many of its anti-inflammatory and pain-relieving effects may occur through these pathways.

Links from this website to any other websites do not constitute an endorsement, inferred or otherwise, of those websites or the content therein, nor do they suggest any endorsement of our website by the external website or its authors. They are provided simply as information that may be of interest to our visitors unless explicitly stated otherwise.

Researchers in New Zealand have studied whether cannabis can be used to treat severe motor and vocal tics in those suffering from Tourette syndrome. The study concluded that subjects who took a controlled THC-CBD medicated spray showed marked improvement in the frequency and severity of motor and vocal tics post-treatment. Although the study is only a small clinical trial, it is one of the first to specifically analyze the effects of cannabis on Tourette syndrome.
The effects of marijuana on each person depend on the type of cannabis and how much THC it contains, the way the drug is taken (by smoking or eating), the experience and expectations of the user, the setting where the drug is used, and whether alcohol or other drugs are also being used. Some people feel nothing at all when they first try marijuana; others may feel high (intoxicated and/or euphoric).
The situation isn’t much better in the UK; there are so many legal grey areas surrounding cannabis in hemp and CBD form that nobody knows the full extent of the law today. CBD oil is completely legal in the UK, but there is apparent illegality surrounding the possession of hemp flowers. This article is a good read for looking at cannabis laws (including hemp and CBD) in the UK
The leaves have a peculiar and diagnostic venation pattern that enables persons poorly familiar with the plant to distinguish a cannabis leaf from unrelated species that have confusingly similar leaves (see illustration). As is common in serrated leaves, each serration has a central vein extending to its tip. However, the serration vein originates from lower down the central vein of the leaflet, typically opposite to the position of, not the first notch down, but the next notch. This means that on its way from the midrib of the leaflet to the point of the serration, the vein serving the tip of the serration passes close by the intervening notch. Sometimes the vein will actually pass tangent to the notch, but often it will pass by at a small distance, and when that happens a spur vein (occasionally a pair of such spur veins) branches off and joins the leaf margin at the deepest point of the notch. This venation pattern varies slightly among varieties, but in general it enables one to tell Cannabis leaves from superficially similar leaves without difficulty and without special equipment. Tiny samples of Cannabis plants also can be identified with precision by microscopic examination of leaf cells and similar features, but that requires special expertise and equipment.[12]
CBD oil alleviates physical pain and anxiety – both of which can have a negative impact on sleep. Additionally, CBD oil can actually prolong sleep for some, leading to more rest from night to night. Most medical experts agree that marijuana is not particularly beneficial for individuals with medical conditions and/or mental health disorders, as the THC can increase their symptoms; this makes CBD oil a good alternative option for people with the following sleep disorders and medical conditions.
In 2014, President Obama signed the Farm Bill of 2014 into law. This law contained a section that removed hemp from Schedule 1 of the Controlled Substances Act. It also created a legal structure that made cultivation and research of hemp legal in states that wanted to initiate “Pilot Research Programs” into the cultivation and marketing of hemp and hemp-derived products.
Since the beginning of the 20th century, most countries have enacted laws against the cultivation, possession or transfer of cannabis.[220] These laws have impacted adversely on cannabis cultivation for non-recreational purposes, but there are many regions where handling of cannabis is legal or licensed. Many jurisdictions have lessened the penalties for possession of small quantities of cannabis so that it is punished by confiscation and sometimes a fine, rather than imprisonment, focusing more on those who traffic the drug on the black market.
Several hundred million years ago mosses and their kin went one way, evolutionarily speaking, and the lineage of trees and flowering plants went the other. Somehow, in the vast expanse of geologic time that followed, a few members of these distantly related groups in the plant kingdom copied one another in making something of great interest to humans: the psychoactive chemical, or cannabinoid, that gets people high.
When formulating a CBD regimen for a specific disease or illness (like chronic or neurological pain), it’s important to understand that CBD should be used regularly for maximum relief. Meaning it should be used as a preventative first – it can also be used to manage acute flare ups, but the preventative maintenance is most important! Think about it like any other dietary supplement, you want to establish a baseline concentration in your system.
^ Fusar-Poli, Paolo; Crippa, José A.; Bhattacharyya, Sagnik; Borgwardt, Stefan J.; Allen, Paul; Martin-Santos, Rocio; Seal, Marc; Surguladze, Simon A.; O'Carrol, Colin; Atakan, Zerrin; Zuardi, Antonio W.; McGuire, Philip K. (2009). "Distinct Effects of Δ9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing". Archives of General Psychiatry. 66 (1): 95–105. doi:10.1001/archgenpsychiatry.2008.519. PMID 19124693.

Wikidata: Q79817 Wikispecies: Cannabis APDB: 189080 APNI: 106875 BioLib: 3465 EoL: 72695 EPPO: 1CNIG FloraBase: 22595 FNA: 105522 FoC: 105522 GBIF: 2984538 GRIN: 2034 iNaturalist: 72032 IPNI: 40737-1 IRMNG: 1280947 ITIS: 19108 NBN: NHMSYS0000456774 NCBI: 3482 NZOR: 5344e3b5-4049-474a-ac38-eb23ffc8f216 PLANTS: CANNA POWO: urn:lsid:ipni.org:names:30204649-2 Tropicos: 40000735 uBio: 4894539 VASCAN: 945


Despite the fact that Cannabis was grown on a large scale in many countries, the abuse as a narcotic remained uncommon in Western countries until relatively recently. People were largely unaware of the psychoactive properties of Cannabis and it is unlikely that early cultivars, selected mainly for their seed or fiber qualities, contained significant amounts of the psychoactive THC. The medicinal use of Cannabis was introduced in Europe only around 1840, by a young Irish doctor, William O’Shaughnessy, who served for the East India Trading Company in India, where the medicinal use of Cannabis was widespread. Unlike the European fiber Cannabis, these Indian varieties did contain a reasonable amount of bioactive cannabinoids. In the following decades, the medicinal use of Cannabis saw a short period of popularity both in Europe and in the United States. At the top of its popularity, more than 28 different medicinal preparations were available with Cannabis as active ingredient, which were recommended for indications as various as menstrual cramps, asthma, cough, insomnia, support of birth labor, migraine, throat infection, and withdrawal from opium use.27


Check Dr. Stephen Porges’ work, as well as Stanley Rosenburg. Both treat trauma and the vagus nerve’s role in bodily symptoms, which cause a lot of the symptoms you mention, as well as other people here. Some of Stanley Rosenburg’s simple exercises along with Stephen Porges’ work, can realign the vagus nerve and when done regularly have a cumulative effect. Basically, most symptoms, even seizures can be caused by misalignments and/or contracted muscles, (even the tiniest muscle in the human body, the stapedius muscle when chronically contracted can cause havoc on body) all under the umbrella of the vagus nerve (polyvagal nervous system). This is very well researched and is cutting edge treatment without the use of drugs of any kind. Some of Porges’ treatments use music, believe it or not, specially designed headsets with bone conduction. But please research, there are therapists trained in this field and in meantime, you can self-apply Stanley Rosenburg’s Basic Exercise, as well as others, first and you will see drastic results.
It is not surprising that male-associated markers are relatively abundant. In dioecious plants where sex chromosomes have not been identified, markers for maleness indicate either the presence of sex chromosomes which have not been distinguished by cytological methods or that the marker is tightly linked to a gene involved in sex determination.[15]
The main and only ingredient in CBD Pain Cream is Cannabidiol. This comes from the Marijuana plant, which has over 400 chemicals in it. Now, this won’t get you high, as it contains no THC. And, CBD is completely legal in all 50 states. Truly, CBD is a breakthrough for reducing pain, inflammation from chronic conditions, and even stress. † And, now you can get in in a convenient topical cream to help erase the pain right on the spot. Within a few minutes, you should notice your pain disappearing. And, CBD Pain Cream saves you from having to be dependent on prescriptions. †

^ "Fats and fatty acids contents per 100 g (click for "more details") example: avocado oil; user can search for other oils". Nutritiondata.com, Conde Nast for the USDA National Nutrient Database, Standard Release 21. 2014. Retrieved 7 September 2017. Values from Nutritiondata.com (SR 21) may need to be reconciled with most recent release from the USDA SR 28 as of Sept 2017.

If you live in a state where CBD is legal for your condition, it’s best to buy it from a state-regulated dispensary. But even there, oversight is uneven. “I feel safe being a cannabis consumer in Colorado, since the state tracks everything from seed to sale, but I didn’t the first few years after cannabis became legal,” when the rules were still taking shape, says Robyn Griggs Lawrence, the Boulder author of The Cannabis Kitchen Cookbook, which features recipes for cannabis edibles.
I have a brother in law who has been diagnosed with cataplexy and narcoplexy, where he starts quivering and slowly loses control of his body and goes into a sleep, which causes him to drop to the ground with mild seizures while he is out. He lives alone (59 years old), but has smoked cannabis since he (we) were teenagers. He still smokes, and is on medication twice a day for this condition, but if he misses those meds by even half an hour, he is at risk of these seizures. The sad part is, these seizures are usually brought on by the smallest emotional change, usually tension, excitement or, the worst thing, if something he finds funny and is the least bit tickled about and starts to laugh, this process will immediately begin. Does anyone know if this kind of condition is treatable with cbd oil’s or concentrates? As I said, he smokes weed, and often grows his own, but he does it for the high and relaxation advantage, since he is basically home-bound due to this condition ending his work career about 4 years ago. Thanks for any replies. I’d be overjoyed if I could tell him there’s a possible solution to the problem other than his prescriptions. Or even if it worked WITH his meds to keep from having to live such a sedentary life.
     Marijuana oil has been a hot topic over the last few years as many states pass medical Marijuana programs and more and more reports come filtering out of them regarding the therapeutic potentials offered by various extracts featuring high levels of Cannabinoids such as CBD (Cannabidiol), one of the main active substances contained within Cannabis. Dramatic cases featured on such noteworthy TV shows as the Dr. Sanjay Gupta CNN specials that first brought strains such as Charlotte's Web into the national spotlight have done much to raise public awareness of CBD.
I have arthritis in many joints of one foot and at times it can be very painful walking. Ordered some 500mg CBD pain cream. It arrived within a few days. It was amazing how quickly I felt relief after I rubbed it in. Slight odor but not objectionable. I cannot use products with camphor, as they make my skin feel like it is on fire. This is great! Thank you!
I’ve been wanting to know on how to understand the life cycle of a marijuana plant but I don’t know how to get started. I do research on my own, I also read lots of articles but this one caught my attention https://www.bonzaseeds.com/blog/life-cycle-marijuana-plant/ It has the content of all you about to know in planting and to understand the life cycle of marijuana plant.
CBD Oil can also contain ZERO amount of THC. If this were coffee, it’s all in the grind. It still is, figuratively, for hemp CBD oil. We developed a product from listening to our customers that needed 100% certainty their oil didn’t contain trace amounts of THC. Like who? First responders, athletes, military personnel, or anyone that wants 100% confidence they’re consuming only CBD. Read more about it here.
In short, the results of the survey (which were published in the Journal of Pain Research) showed that roughly 42% and 46% (respectively) of participants claimed they were able to use cannabis in place of traditional medical to effectively treat their specific medical ailment. So if you’re wondering how to know if you need CBD for pain, remember that you’re certainly not alone.
Anecdotal evidence from patients is becoming increasingly widespread as well. Morgan Freeman suffers from pain and he was quoted saying, “I have fibromyalgia pain in my arm and the only thing that offers any relief is marijuana.” Whoopi Goldberg also uses cannabis to treat her daily pain from glaucoma and has even launched a line of medical cannabis products geared towards women suffering from menstrual pain.
Cannabidiol (CBD) is a subclass of Phytocannabinoids and one among one twenty cannabis compounds. It is hailed for its ability to be meditative, without causing a euphoric high. This non-addictive miracle cannabinoid has been the talk of the town and the core of numerous experiments. The anti-inflammatory properties of CBD have inspired the marketing of its by-products, such as CBD oil, for pain relief and relaxation.
In general, the human body has specific sites that are allotted to cannabinoids, called the cannabinoid receptor sites. Receptors are mechanisms to which the cannabinoids naturally present in the human body as well as the ones artificially ingested/ applied attach themselves. There are two kinds of receptors for cannabinoids, the CB1, and the CB2. While the CB1 receptors are present in the brain, the CB2 receptors can be found in the immune system.

Cannabidiol can be taken into the body in multiple different ways, including by inhalation of cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as CBD oil containing only CBD as the active ingredient (no added tetrahydrocannabinol [THC] or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution.[2] CBD does not have the same psychoactivity as THC,[9][10][11] and may affect the actions of THC.[7][8][9][12] Although in vitro studies indicate CBD may interact with different biological targets, including cannabinoid receptors and other neurotransmitter receptors,[9][13]as of 2018 the mechanism of action for its biological effects has not been determined.[8][9]
Carbon dioxide is passed through the plant material at a very specific temperature and pressure. Carbon dioxide, which is normally a gas at (or above) room temperature, can be pressurized until it becomes so dense that it takes on some of the properties of a liquid while still maintaining the fluid dynamics of a gas. In this state, CO2 is known as a supercritical fluid.
^ A 2016 review also found a statistically significant increase in crash risk associated with marijuana use, but noted that this risk was "of low to medium magnitude."[73] The increase in risk of motor vehicle crash for cannabis use is between 2 and 3 times relative to baseline, whereas that for comparable doses of alcohol is between 6 and 15 times.[74]
Particular difficulties face the clinician managing intractable patients afflicted with cancer-associated pain, neuropathic pain, and central pain states (eg, pain associated with multiple sclerosis) that are often inadequately treated with available opiates, antidepressants and anticonvulsant drugs. Physicians are seeking new approaches to treatment of these conditions but many remain concerned about increasing governmental scrutiny of their prescribing practices (Fishman 2006), prescription drug abuse or diversion. The entry of cannabinoid medicines to the pharmacopoeia offers a novel approach to the issue of chronic pain management, offering new hope to many, but also stoking the flames of controversy among politicians and the public alike.
In 2014, President Obama signed the Farm Bill of 2014 into law. This law contained a section that removed hemp from Schedule 1 of the Controlled Substances Act. It also created a legal structure that made cultivation and research of hemp legal in states that wanted to initiate “Pilot Research Programs” into the cultivation and marketing of hemp and hemp-derived products.
Although it’s a relatively new product in the CBD hemp oil industry, CBD isolate extraction and CBD isolate ingestion is taking the cannabinoid market by storm, becoming increasingly popular with retail customers, formulators, and wholesalers alike. Its many uses and applications in this unmodified form are almost endless and its versatility unparalleled. Plus, you are put in complete control of exactly how much CBD goes into each serving but not matter how much you use it will not get you high.
One area where CBD is clearly helpful: the treatment of seizures associated with one form of epilepsy. A 2017 New England Journal of Medicine study found ingesting oral CBD dramatically cut down most patients’ seizure frequency—a finding that prompted the FDA to support the approval of one CBD drug for use in the treatment of some epilepsy patients.
Cannabis has held sacred status in several religions. It has been used in an entheogenic context – a chemical substance used in a religious, shamanic, or spiritual context[58] - in the Indian subcontinent since the Vedic period dating back to approximately 1500 BCE, but perhaps as far back as 2000 BCE. There are several references in Greek mythology to a powerful drug that eliminated anguish and sorrow. Herodotus wrote about early ceremonial practices by the Scythians, thought to have occurred from the 5th to 2nd century BCE. In modern culture the spiritual use of cannabis has been spread by the disciples of the Rastafari movement who use cannabis as a sacrament and as an aid to meditation. The earliest known reports regarding the sacred status of cannabis in the Indian subcontinent come from the Atharva Veda estimated to have been written sometime around 2000–1400 BCE.[59]

The ultimate goal of all drug-abuse treatment is to enable people to achieve lasting abstinence, but the immediate goals are to reduce drug use, improve the person's ability to function, and minimize medical and social complications. Like people with diabetes or heart disease, people in treatment for drug addiction will need to change behaviors to adopt healthier lifestyles.
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
This does nothing for me. I have been taking between 4 and 8 Aleeve a day for back pain related to kyphosis and hoped this would help me cut down on those medications. This is hemp oil, not CBD oil. After trying this and receiving no results I switched to CBD oil from a well reviewed company and the CBD oil is helping. I now take the CBD oil twice a day and have noticeable results. I have cut my regular pain meds to one or two a day.
And the final nail in industrial hemp’s proverbial coffin: Federal law in the United States prohibits the use of hemp leaves and flowers to make drug products. That said, isolating CBD nullifies these distinctions, rendering its source irrelevant as CBD isolate contains nothing but CBD. In this case, the differences between industrial hemp and whole-plant marijuana are far less significant.

Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.
RSHO™ CBD hemp oil is available in four varieties of high-quality, pure cannabidiol oil, including Green Label, Blue Label, Gold Label, and Special Blend. RSHO™ contains between 50mg and 190mg of cannabidiol per 0.5 gram serving. Each of the pure CBD hemp oil varieties come in 3 gram and 10 gram applicators. For regular users, 3 packs and 6 packs of applicators are available.
Carbon dioxide is passed through the plant material at a very specific temperature and pressure. Carbon dioxide, which is normally a gas at (or above) room temperature, can be pressurized until it becomes so dense that it takes on some of the properties of a liquid while still maintaining the fluid dynamics of a gas. In this state, CO2 is known as a supercritical fluid.
Although hemp and marijuana are essentially different cultivars of the same plant – Cannabis sativa L – marijuana has been cultivated to concentrate high levels of THC (frequently as much as 18%), in the plant’s flowering tops, whereas hemp, which is primarily grown in Europe to make clothing, paper, biofuels, bioplastics, nutritional supplements, cosmetics, and foods, contains less than 0.3% THC.

NuLeaf Naturals CBD oil tinctures are all full spectrum; it is 100% organic and never made with herbicides, pesticides, or chemical fertilizers. The brand offers a full spectrum pet CBD oil tincture, as well. NuLeaf Naturals offers free shipping to all 50 states; the brand’s products are also sold in more than 1,000 retail locations across the country.
Since the demand for CBD has increased, so has the number of overseas companies who are selling CBD products. The problem is, many of their products have been found to contain chemicals, heavy metals, and toxins. The companies in China and Eastern Europe, in particular, have been selling low-quality CBD items that could potentially do you more harm than good.
The ultimate goal of all drug-abuse treatment is to enable people to achieve lasting abstinence, but the immediate goals are to reduce drug use, improve the person's ability to function, and minimize medical and social complications. Like people with diabetes or heart disease, people in treatment for drug addiction will need to change behaviors to adopt healthier lifestyles.
people don’t use CBD for recreational use. it has little to no THC so has no psychoactive properties. many CBD products processed from hemp also do not have enough CBD to affect any medical disorders either. they are just jumping on the trendy CBD bandwagon, like many other so-called “nutritional supplements”. so it is very difficult to find and trust the CBD processed form hemp. useful CBD from hemp can only be processed from the flowers, which is still illegal, even though no THC. the only legal use of hemp in the states is for “industrial” use, only the stalks and seeds (fiber and oil). the stalks and seeds of hemp are so lacking in usable CBD that it is not legitimate for medical use.
The move to Whole Plant extracts will mark an important change in the market as Whole Plant extracts derived from the flowers of the female Hemp plants are able to offer superior Cannabinoid and Terpene profiles as well as higher concentrations of base Cannabinoids, making them similar in composition/concentration to traditional Marijuana Oil extracts derived from illicit Marijuana. A look inside of one of the nations earliest whole plant CBD Hemp pilot programs producing cannabis oil legal for sale may be seen here.

Dispensaries: In states where marijuana is legal for recreational use, dispensaries are a common sight. They are much rarer in states with more restrictions. In states that permit the use of medical marijuana, hemp-based CBD oils do not normally require a prescription but marijuana-based oils do. Like brick-and-mortar locations, dispensaries offer more customer service. However, as noted, this may not be an option depending on the buyer’s state of residence. Also, CBD oil prices tend to be significantly higher at dispensaries.
^ Jump up to: a b c d Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389. PMC 3481531. PMID 23108553.
CBD strains can be consumed just as you would THC strains. You can smoke or vaporize CBD-rich flower, eat a CBD-infused edible, swallow a CBD oil capsule, apply a CBD lotion, or use a CBD tincture sublingually. Hemp products also contain CBD, though it is a less efficient source and lacks the beneficial chemical diversity of cannabis-derived CBD products (more on that here).

Ok, this is seriously gold! Best $12 spent in a while! It’s a topical cbd ointment for pain relief. I tried it on my knees to see if it helped the arthritis pain and omg did it! One application lasted like 4.5 hrs and unlike most pain relief creams, it didn’t stay goopy or sticky on my skin! It’s more watery than other creams and it soaked in quickly. Skin was dry but nice and cool from the menthol in it. I seriously recommend it to anyone who deals with RA pain like I do!!!! I’ve never had an over the counter cream work so good in the 20 something years I’ve been diagnosed! Since getting myself off of pain pills and going the “natural” route in pain management, I’m way happier without the harsh side effects and reactions that narcotic pills gave me.


Medical marijuana in the U.S. is controlled at the state level. Per federal law, cannabis is illegal as noted in the Controlled Substances Act, but the federal government has stated they will not actively prosecute patients and caregivers complying with state medical marijuana laws. However, use of medical marijuana outside of the state laws for illegal use or trafficking will not be tolerated by state or federal government.


Inhibited liver function: The liver regulates the way different drugs are metabolized within the body; this process is known as hepatic drug metabolism. Higher-than-average doses of CBD oil can slow the hepatic drug metabolism process. As a result, users may not be able to process other drugs as quickly. This is particularly concerning for CBD oil users who also take prescription medications.

Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.

×