Given the opioid crisis, physicians are less likely to lead with narcotics, and some of us are deciding not to prescribe them altogether. The problem with narcotics is that they work. They work really well. Sometimes too well, leading to a patient becoming so comfortable they “forget” to breathe. So, while reducing the amount of narcotics prescribed to patients is a good thing, the problem is physicians don’t have a lot of good alternatives to recommend to their patients, until now.
As of 2018, there are a total of 46 states (including the 8 states mentioned above) where CBD is legal with a prescription for medicinal usage. Now although CBD usage is for legal in these states, the law varies from state to state, with 17 states having specific legislation for the THC-levels found in CBD and the conditions being treated with CBD.
Cannabidiol is currently a class B1 controlled drug in New Zealand under the Misuse of Drugs Act. It is also a prescription medicine under the Medicines Act. In 2017 the rules were changed so that anyone wanting to use it could go to the Health Ministry for approval. Prior to this, the only way to obtain a prescription was to seek the personal approval of the Minister of Health.
A 2015 review found that the use of high CBD-to-THC strains of cannabis showed significantly fewer positive symptoms such as delusions and hallucinations, better cognitive function and both lower risk for developing psychosis, as well as a later age of onset of the illness, compared to cannabis with low CBD-to-THC ratios. A 2014 Cochrane review found that research was insufficient to determine the safety and efficacy to using cannabis to treat schizophrenia or psychosis. As of 2017, the molecular mechanisms for the anti-inflammatory and possible pain relieving effects of cannabis are under preliminary research.
After revisions to cannabis scheduling in the UK, the government moved cannabis back from a class C to a class B drug. A purported reason was the appearance of high potency cannabis. They believe skunk accounts for between 70 and 80% of samples seized by police (despite the fact that skunk can sometimes be incorrectly mistaken for all types of herbal cannabis). Extracts such as hashish and hash oil typically contain more THC than high potency cannabis flowers.
A 2011 study evaluated the effects of two non-psychoactive cannabinoids, cannabidiol (CBD) and cannabichromene (CBC), on pain management. The study concluded that, “CBD and CBC stimulated descending pathways of antinociception and caused analgesia by interacting with several target proteins involved in nociceptive control. These compounds might represent useful therapeutic agents with multiple mechanisms of action.”
Refined hempseed oil is clear and colorless, with little flavor and lacks natural vitamins and antioxidants. Refined hempseed oil is primarily used in body care products. Industrial hempseed oil is used in lubricants, paints, inks, fuel, and plastics. Hempseed oil is used in the production of soaps, shampoos and detergents. The oil has a 3:1 ratio of omega-6 to omega-3 essential fatty acids. It may also be used as a feedstock for the large-scale production of biodiesel.
If you have fibromyalgia, then you’ve probably heard of the rave reviews people post online about CBD’s effect on it. For those of you who don’t know, fibromyalgia is a type of chronic disorder that causes widespread muscle pain, pain in the bones, and general fatigue. Since the measure of pain is subjective, it cannot be recorded or measured by tests.
There is a lot of excitement about hemp oil these days. There is also a lot of confusion. While many people have heard of hemp oil, they aren’t exactly sure what it does. Or whether or not it contains THC, the psychoactive ingredient in marijuana. Will hemp oil make you “high”? If you use a hemp oil supplement are you breaking any laws? The following are answers to some of the most frequently asked questions about hemp oil.
PTSD causes intense anxiety and fear, and it is caused by severe trauma (such as a frightening event, war, car accident, etc.). Whatever the cause, PTSD can cause intense stress that interferes with normal life. But thanks to the calming effect of CBD, supplementing with a CBD tincture can be a way to normalize the nervous system and reduce anxiety.
I have a slightly bulging disc in my back that has been causing neuropathy in my left leg for years. I’ve had several rounds of trigger point injections; see a physical therapist regularly, and lately a chiropractor as well. The next step for me would be to try an epidural pain block. Several of my other doctors are big proponents of the “inflammation as a cause of disease” theory and have really encouraged me to do things to reduce inflammation. Omega-3 fatty acids in particular help with this (as most Americans consume a poor ratio of omega-6 to omega-3 which can increase inflammation.) Hemp products contain phytocannabinoids, a substance that can help decrease pain and inflammation. This is full spectrum hemp oil derived from hemp seeds—meaning it contains all of the phytocannabinoids and not just one in particular. This is NOT CBD (cannabidiol) oil, although based on my research it likely contains low levels of CBD. CBD is the substance produced from hemp flowers (a plant with little to no THC—the substance that causes a high) (or marijuana flowers—a plant in the same family with significant THC) that is widely known to have medicinal purposes in pain relief, stopping seizures, etc.
Pure CBD hemp oil is extracted from the cannabis varieties that are naturally abundant in CBD, and low in THC. A specialized extraction process is used to yield highly concentrated CBD oil or pure cannabidiol that also contains other nutritious material such as omega-3 fatty acids, terpenes, vitamins, chlorophyll, amino acids, and other phytocannabinoids like cannabichromene (CBD), cannabigerol (CBG), cannabinol (CBN) and cannabidivarian (CBCV).
The FDA relies on applicants and scientific investigators to conduct research. Our role, as outlined in the Federal Food, Drug, and Cosmetic Act, is to review data submitted to the FDA in a marketing application to determine whether a proposed drug product meets the statutory standards for approval. Additional information concerning research on the medical use of marijuana is available from the National Institutes of Health, particularly the National Cancer Institute (NCI) and NIDA.
According to the United Nations Office on Drugs and Crime (UNODC), "the amount of THC present in a cannabis sample is generally used as a measure of cannabis potency." The three main forms of cannabis products are the flower, resin (hashish), and oil (hash oil). The UNODC states that cannabis often contains 5% THC content, resin "can contain up to 20% THC content", and that "Cannabis oil may contain more than 60% THC content."
What a great article on CBD oils which only touches the surface of its benefits!! Only thing I disagree upon is it mentions CBD not containing any psychotropics. CBD oil requires a touch of THC to properly work. If the solution is strong enough and people take more than necessary one can get s little “high” for reals. A tiny amount of CBD oil goes a long way, especially when you have the oils directly produced from squeezing the oils from CBD prominent plants. Sativa plants often have a higher THC component than Indica plants and Sativa plants are smoked for their “get up and go properties “ rather than the more relaxing kick back Indica plants
According to researchers, 25 percent of all cancer patients use medical marijuana. Cancer patients are finding relief from medical cannabis. And they want to know more about it. Research conducted at St. George’s University of London, found the two most common cannabinoids in marijuana, tetrahydrocannabinol (THC) and cannabidiol (CBD), weakened the ferocity of cancer cells and made them more susceptible to radiation treatment. Other studies have shown that medical marijuana treatments can slow the growth of cancer cells and halt their spread to other parts of the body.
The glutamatergic system is integral to development and maintenance of neuropathic pain, and is responsible for generating secondary and tertiary hyperalgesia in migraine and fibromyalgia via NMDA mechanisms (Nicolodi et al 1998). Thus, it is important to note that cannabinoids presynaptically inhibit glutamate release (Shen et al 1996), THC produces 30%–40% reduction in NMDA responses, and THC is a neuroprotective antioxidant (Hampson et al 1998). Additionally, cannabinoids reduce hyperalgesia via inhibition of calcitonin gene-related peptide (Richardson et al 1998a). As for Substance P mechanisms, cannabinoids block capsaicin-induced hyperalgesia (Li et al 1999), and THC will do so at sub-psychoactive doses in experimental animals (Ko and Woods 1999). Among the noteworthy interactions with opiates and the endorphin/enkephalin system, THC has been shown to stimulate beta-endorphin production (Manzanares et al 1998), may allow opiate sparing in clinical application (Cichewicz et al 1999), prevents development of tolerance to and withdrawal from opiates (Cichewicz and Welch 2003), and rekindles opiate analgesia after a prior dosage has worn off (Cichewicz and McCarthy 2003). These are all promising attributes for an adjunctive agent in treatment of clinical chronic pain states.
CBD content in Hemp oil, when extracted from the proper strains, can be very high as Hemp plants are now the very strains that are being used to breed high CBD levels back into Cannabis after years of selective recreational breeding for high THC values. Well known strains such Charlotte's Web are hybrids that were selected from crosses with High CBD Hemp varietals and those Hemp genetics are what account for the new High CBD Strains of Marijuana and commercial Hemp that have and are being developed.
The reason so many people are interested in cannabis products that don’t make them high, proponents say, is that CBD helps with everything from pain and nausea to rheumatoid arthritis, cancer, Crohn’s disease, and dementia. CBD is anti-inflammatory, anti-anxiety, antibacterial, immunosuppressive, and more, says Joseph Cohen, D.O., a cannabis doctor in Boulder, CO.
It’s easy to see why vaping has become such a popular method for consuming marijuana. The method is remarkably discrete and produces none of the telltale “weed smells” that often betray cannabis users. Vape pens and other hand-held devices are portable and convenient. They’re free of many of the harsh marijuana plant compounds that can harm your lung health, like tars. And companies are getting better at crafting high-quality, flavorful vape cartridges with a wide array of cannabinoid profiles.
Final thoughts: Hemp oil and hemp derived CBD oil is legal in all fifty states, but there certainly is a stigma to it. Because of that it can be very hard to find reliable information to educate yourself with. This is a great dietary supplement and may help decrease inflammation, improve skin, help with mild pain, etc. If you have severe pain, hemp derived CBD oil may be what you need.
That being said, it was unlikely that the federal government was interested in pursuing individuals complying with state-mandated regulations surrounding legalized cannabis for recreational use, although the CSA law still gives them authority to do so. However, the new Trump administration may change this thinking and users of legal marijuana and legal dispensaries await further action and clarifying rules.
In a Phase II double-blind, randomized, placebo-controlled, 5-week study of 56 rheumatoid arthritis patients with Sativex (Blake et al 2006), employed nocturnal treatment only to a maximum of 6 sprays per evening (16.2 mg THC + 15 mg CBD). In the final treatment week, morning pain on movement, morning pain at rest, DAS-28 measure of disease activity, and SF-MPQ pain at present all favored Sativex over placebo (Table 1).
The FDA has approved Epidiolex, which contains a purified drug substance cannabidiol, one of more than 80 active chemicals in marijuana, for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome in patients 2 years of age and older. That means the FDA has concluded that this particular drug product is safe and effective for its intended indication.
2015 and beyond will bring many exciting changes to the current High CBD Hemp oil market. The Hemp plant once again being cultivated domestically for the first time in decades, will allow for companies producing Cannabidiol Rich Hemp products to source their base material from domestic suppliers, raising the bar on many of the current offerings that are using imported Hemp base from Europe from commercial strains that just happened to have decent CBD levels rather than strains actually developed to have high CBD levels, that are grown out seedlessly like traditional Marijuana for the strongest concentrations of Cannabindoids, such as those found within Marijuana oil.
Confusion about the difference between hemp and cannabis oil has spiked recently due to the increase of cannabis-based products available on the market. Variety is a great thing considering every individual requires different concentrations and delivery methods. If you are new to cannabis vape oils or products, it can be difficult to know what is what.
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, M.D., clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger. This is why Amanda Oliver, 31, a career consultant in Charleston, SC, pops a CBD gummy bear each night before bed. “I used to lie there tossing and turning as my mind raced from work projects to whether I had set the home alarm,” Oliver says. One piece of candy with 15 mg of CBD is enough to shut off her brain and facilitate sleep. She also swears by the CBD oil she takes at the height of her period, which she says quells her debilitating cramps.