Marijuana.com informs, engages and grows the cannabis community through coverage of marijuana law + politics, science + medicine, consumer trends, culture and commentary. The site also offers a forum for discussion of current events and issues of interest. Marijuana.com has been in operation since 1995 and is owned and operated by Weedmaps.com, the most widely used medical and recreational marijuana dispensary locator in the industry.
Did you know that pain is the number one reported condition for medical marijuana cards in the U.S.? In Colorado alone, 92% of patients, over 86,000 people, use cannabis to treat their chronic pain. Research on CBD and pain management has shown great promise and people are increasingly turning to cannabinoid therapy as the harms of opioids garner more attention and scrutiny.
A. The Agriculture Improvement Act of 2018 changes certain federal authorities relating to the production and marketing of hemp, defined as cannabis (Cannabis sativa L.), and derivatives of cannabis with extremely low (less than 0.3 percent on a dry weight basis) concentrations of the psychoactive compound delta-9-tetrahydrocannabinol (THC). These changes include removing hemp from the Controlled Substances Act, which means that it will no longer be an illegal substance under federal law. However, Congress explicitly preserved the agency's current authority to regulate products containing cannabis or cannabis-derived compounds under the FD&C Act and section 351 of the Public Health Service Act. Please see the FDA’s statement on the signing of the Agriculture Improvement Act of 2018.
© Copyright 2018. Miji Media LLC. All Rights Reserved. These statements have not been evaluated by the Food and Drug Administration. The products mentioned on this site are not intended to diagnose, treat, cure or prevent any disease. As the consumer, it is your responsibility to know your local, state and federal laws before making any purchases. All products on this website are intended for legal use. Prior to purchasing a product(s) on this website, you should confirm legality of the product in the state where you request shipment.
Interestingly, CBD oil protects the body against its own euphoric stimulant. An endogenous cannabinoid, Anandamide, is produced on demand by the human body. ‘Ananda’, in Sanskrit, means ‘bliss’. Anandamide, thus, creates a runner’s high, and this is regulated by Cannabidiol. Thus, we feel falsified pleasureless, on the use of cannabidiol or CBD oil.

Now 13, Jackson — whose diagnosis is undetermined — continues to use marijuana every day. (Like many patients, he ingests it in droplet form, which allows for more precise dosing and avoids lung problems.) He still has seizures, but they are less severe and they occur once every week or two, down from around 200 a month before he started using cannabis. He is back in school full time and is well enough to go on hikes and bike rides with his family.

^ Vanyukov MM, Tarter RE, Kirillova GP, Kirisci L, Reynolds MD, Kreek MJ, Conway KP, Maher BS, Iacono WG, Bierut L, Neale MC, Clark DB, Ridenour TA (June 2012). "Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective". Drug and Alcohol Dependence (Review). 123 Suppl 1: S3–17. doi:10.1016/j.drugalcdep.2011.12.018. PMC 3600369. PMID 22261179.


The leaves have a peculiar and diagnostic venation pattern that enables persons poorly familiar with the plant to distinguish a cannabis leaf from unrelated species that have confusingly similar leaves (see illustration). As is common in serrated leaves, each serration has a central vein extending to its tip. However, the serration vein originates from lower down the central vein of the leaflet, typically opposite to the position of, not the first notch down, but the next notch. This means that on its way from the midrib of the leaflet to the point of the serration, the vein serving the tip of the serration passes close by the intervening notch. Sometimes the vein will actually pass tangent to the notch, but often it will pass by at a small distance, and when that happens a spur vein (occasionally a pair of such spur veins) branches off and joins the leaf margin at the deepest point of the notch. This venation pattern varies slightly among varieties, but in general it enables one to tell Cannabis leaves from superficially similar leaves without difficulty and without special equipment. Tiny samples of Cannabis plants also can be identified with precision by microscopic examination of leaf cells and similar features, but that requires special expertise and equipment.[12]
Put simply, “indica” strains are those associated with a strong body-high, feelings of sedation and relaxation. For this reason, indicas are often thought of as the “heavier” strains of cannabis, offering stronger highs that impact the whole body. They’re popular among marijuana users as pain relieving and sleep-inducing strains. Indicas are especially popular among medical cannabis patients.
Amendment 64 granted Colorado citizens the use and regulation of marijuana. Passed on November 6, 2012, it included a declaration industrial hemp should be regulated separately from marijuana and that the Colorado General Assembly is “to enact legislation governing the cultivation, processing, and sale of industrial hemp.” Soon after Amendment 64 went into effect, Colorado became the first state to contain certified hemp seed – designated as containing less than .3% THC – as well as free of weeds and disease.
Scott Shannon, M.D., assistant clinical professor at the University of Colorado, recently sifted through patient charts from his four-doctor practice to document CBD’s effects on anxiety. His study, as yet unpublished, found “a fairly rapid decrease in anxiety scores that appears to persist for months,” he says. But he says he can’t discount a placebo effect, especially since “there’s a lot of hype right now.”

Hemp oil is a great source of high-quality nutrients and has a long history of use in Eastern culture as a multi-purpose natural remedy. Despite its widespread popularity, prejudice related to its association with Marijuana it has kept it from common use in the West. While Hemp oil contains virtually no THC (the psychoactive element in cannabis) hemp oil is still concerning to some. Thankfully, education is prevailing and the market for hemp oil is growing in the United States, with an increasing number of people seeking it out for its reported health benefits.

Doctors advise pregnant women not to use any drugs because they might harm the growing fetus. Although one animal study has linked marijuana use to loss of the fetus very early in pregnancy, two studies in humans found no association between marijuana use and early pregnancy loss. More research is necessary to fully understand the effects of marijuana use on pregnancy.
Success stories like Oliver’s are everywhere, but there’s not a lot of data to back up those results. That’s because CBD comes from cannabis and, like nearly all other parts of the plant, is categorized by the Drug Enforcement Agency (DEA) as a Schedule 1 drug—the most restrictive classification. (Others on that list: heroin, Ecstasy, and peyote.) This classification, which cannabis advocates have tried for years to change, keeps cannabis-derived products, including CBD, from being properly studied in the U.S.
Cognitive effects of cannabis have been reviewed (Russo et al 2002; Fride and Russo 2006), but less study has occurred in therapeutic contexts. Effects of chronic heavy recreational cannabis usage on memory abate without sequelae after a few weeks of abstinence (Pope et al 2001). Studies of components of the Halstead-Reitan battery with Sativex in neuropathic pain with allodynia have revealed no changes vs placebo (Nurmikko et al 2007), and in central neuropathic pain in MS (Rog et al 2005), 4 of 5 tests showed no significant differences. While the Selective Reminding Test did not change significantly on Sativex, placebo patients displayed unexpected improvement.
Some users speculate about appropriate dosages or methods of application—including whether or not a small amount of THC boosts CBD’s effects, or whether different methods of administration lead to quicker or more significant effects. Some CBD producers also claim that it has a cumulative effect, and so needs to be used regularly to produce a benefit. But Grant says it’s tough to say at this point exactly how people should (or shouldn’t) be using CBD.

While medical marijuana is grown to be high in CBD for the treatment of specific ailments, the THC content can vary dramatically, sometimes getting as high as the CBD content. For an excellent example of the types of marijuana you may find in a licensed dispensary, see this Strain Book. It shows you the types of plants, the percentages of CBD and THC, and even the taste and effects of the stain.
Currently on the market are a variety of hemp oil products that are naturally abundant in CBD, including organic hemp oil concentrates, tinctures, capsules, gums, lotions, salves, shampoos, and conditioners. Please visit our online shop to find the right CBD hemp oil product for you! For more information on CBD products, have a look at our comprehensive CBD products list to learn more.
In some areas where cannabis use had been historically tolerated, new restrictions were instituted, such as the closing of cannabis coffee shops near the borders of the Netherlands,[221] and closing of coffee shops near secondary schools in the Netherlands.[222] In Copenhagen, Denmark in 2014, mayor Frank Jensen discussed possibilities for the city to legalize cannabis production and commerce.[223]
REM behavior disorder: REM behavior disorder (RBD) is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep. For many, RBD is a symptom of a larger, more serious condition or disorder, such as Alzheimer’s disease or PTSD. CBD oil minimizes the symptoms of RBD, and also alleviates the anxiety and painful symptoms that often accompany disorders that lead to RBD.
The exploding recreational market for marijuana has rapidly popularized many methods of consuming cannabis that was decidedly part of the fringe just a few short years ago. Smoking marijuana remains the most widely embraced method, due to the greater accessibility of marijuana flower. But legal recreational cannabis is introducing many marijuana users to new forms of the drug, especially concentrates and edibles. Here’s a brief overview of the major methods for consuming marijuana. 

The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
The key is to effectively gauge exactly how much CBD oil it takes to start managing your pain. If you start off right away with a maximum dose of a 600 mg tincture, you will have no idea how much of the product it actually took to treat your condition, and how much you wasted (this is also important because you do not want to exceed dosage and end up developing a tolerance to the active cannabinoids).

^ Acj, Zondo (2017-08-02). "Minister of Justice and Constitutional Development and Others v Prince (Clarke, Stobbs and Thorpe Intervening) (Doctors of Life International Inc as Amicus Curiae); National Director of Public Prosecutions and Others v Rubin; National Director of Public Prosecutions and Others v Acton and Others". The Constitutional Court of South Africa.

The FDA’s refusal to allow companies to market CBD as a dietary supplement is based on the fact that federal classification as a dietary supplement requires that a substance has not been authorized for investigation as a new drug or medicine. Since Epidiolex has been studied in clinical trials by GW Pharmaceuticals going back several years now and was granted orphan drug status by the FDA in 2013, CBD cannot therefore be classified as a dietary supplement. Or so the FDA says. But cannabis companies are arguing that they started marketing CBD as a dietary supplement before there were any drug trials involving CBD, such that they should still be allowed to claim dietary supplement status for their products. Thus far however, the FDA isn’t budging on this issue.  
Industrial hemp contains, by weight, far less CBD than CBD-rich cultivars such as Harlequin or Sour Tsunami. This means that producing a single 10 mL dose of CBD would require the cultivation and extraction of far more hemp than it would from whole-plant marijuana; thus raising the risk of exposing users to more contaminants. Hemp is classified as a “bioaccumulator,” or a plant that naturally absorbs toxicants from the soil.
In a study with HIV-positive adult men, blood concentrations of ghrelin and other appetitive hormones (leptin, PYY, and insulin) were tested after having received smoked medicinal cannabis or matched placebo for HIV-associated neuropathic pain. Cannabis administration, as compared to placebo, significantly increased ghrelin concentrations in this study. In addition, leptin and PYY levels were, respectively, increased and decreased, but no impact on insulin levels was found (Riggs et al., 2012).
The leaves have a peculiar and diagnostic venation pattern that enables persons poorly familiar with the plant to distinguish a cannabis leaf from unrelated species that have confusingly similar leaves (see illustration). As is common in serrated leaves, each serration has a central vein extending to its tip. However, the serration vein originates from lower down the central vein of the leaflet, typically opposite to the position of, not the first notch down, but the next notch. This means that on its way from the midrib of the leaflet to the point of the serration, the vein serving the tip of the serration passes close by the intervening notch. Sometimes the vein will actually pass tangent to the notch, but often it will pass by at a small distance, and when that happens a spur vein (occasionally a pair of such spur veins) branches off and joins the leaf margin at the deepest point of the notch. This venation pattern varies slightly among varieties, but in general it enables one to tell Cannabis leaves from superficially similar leaves without difficulty and without special equipment. Tiny samples of Cannabis plants also can be identified with precision by microscopic examination of leaf cells and similar features, but that requires special expertise and equipment.[12]
In order to remove unwanted elements such as fats or waxes, CBD oil is subjected to a process called ‘Winterization’. Refined cannabidiol oil is stirred with alcohol and deep-frozen overnight.  A Butcher funnel or a piece of paper is then used to filter the fats out. Finally, the extracted oil is heated to the boiling point of alcohol so the alcohol evaporates.
The existence of substantial clinical investigations regarding CBD has been made public. For example, two such substantial clinical investigations include GW Pharmaceuticals’ investigations regarding Sativex and Epidiolex. (See Sativex Commences US Phase II/III Clinical Trial in Cancer Pain and GW Pharmaceuticals Receives Investigational New Drug (IND) from FDA for Phase 2/3 Clinical Trial of Epidiolex in the Treatment of Dravet Syndrome ).
About 9% of those who experiment with marijuana eventually become dependent according to DSM-IV (1994) criteria.[77] A 2013 review estimates daily use is associated with a 10-20% rate of dependence.[41] The highest risk of cannabis dependence is found in those with a history of poor academic achievement, deviant behavior in childhood and adolescence, rebelliousness, poor parental relationships, or a parental history of drug and alcohol problems.[137] Of daily users, about 50% experience withdrawal upon cessation of use (i.e. are dependent), characterized by sleep problems, irritability, dysphoria, and craving.[116] Cannabis withdrawal is less severe than withdrawal from alcohol.[138]
A limited number of studies have examined the effects of cannabis smoking on the respiratory system.[88] Chronic heavy marijuana smoking is associated with coughing, production of sputum, wheezing, and other symptoms of chronic bronchitis.[68] The available evidence does not support a causal relationship between cannabis use and chronic obstructive pulmonary disease.[89] Short-term use of cannabis is associated with bronchodilation.[90] Other side effects of cannabis use include cannabinoid hyperemesis syndrome.[91]

Acute effects may include anxiety and panic, impaired attention and memory, an increased risk of psychotic symptoms, [b] the inability to think clearly, and an increased risk of accidents.[68][69][70] Cannabis impaired a person's driving ability, and THC was the drug most frequently found in the blood of drivers who have been involved in vehicle crashes. Those with THC in their system were from three to seven times more likely to be the cause of the accident than those who had not used either cannabis or alcohol, although its role is not necessarily causal because THC stays in the bloodstream for days to weeks after intoxication.[71][72][c]


Dry mouth: As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth (or cottonmouth). This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation. In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth.
While in all of these states recreational marijuana remains illegal, Connecticut, Delaware, Illinois, Maryland, Minnesota, Mississippi, Missouri, Nebraska, New Hampshire, New York, North Carolina, Ohio and Rhode Island have all decriminalized the drug. In these states, having smaller amounts of marijuana on you won't lead to an arrest or a criminal record. The maximum amount you're allowed to have on your person will vary by state.
It is for this reason that all the finished hemp goods that you see for sale in America, from food products to clothing to building materials, are part of an imported hemp industry that has surpassed $688 million annually. The size of this import industry is one of the major catalysts for hemp legalization in the U.S. As a renewable source of a range of products, hemp provides an exciting new step in American agriculture.
Cannabis has mental and physical effects, such as creating a "high" or "stoned" feeling, a general change in perception, heightened mood, and an increase in appetite.[21][22] Onset of effects is within minutes when smoked, and about 30 to 60 minutes when cooked and eaten.[21][23] They last for between two and six hours.[23] Short-term side effects may include a decrease in short-term memory, dry mouth, impaired motor skills, red eyes, and feelings of paranoia or anxiety.[21][24][25] Long-term side effects may include addiction, decreased mental ability in those who started as teenagers, and behavioral problems in children whose mothers used cannabis during pregnancy.[21] There is a strong relation between cannabis use and the risk of psychosis,[26] though the cause-and-effect is debated.[27]

Millions of people in the world suffer from joint pain, back pain, arthritis and other bone and joint related problems. Along with the pain, there is also inflammation and stiffness in the joints, which makes movements quite difficult and restricted. Infact when the pain and stiffness is high, it might lead to the person becoming almost crippled. There are many joint pain relievers in the form of oils, gels, ointments etc. But in most of them, the pain subsides temporarily and come back again in full force. Some of them might also have side effects on the skin. CBD Balm needs special mention in this case as product has shown to have remarkable results for treating joint pain and related problems.


     While these CDB laws are well intentioned and make certain types of cannabis oil legal in certain states, many of them are extremely exclusive as to what illnesses may qualify patients for use, and limit production of the plant—in most cases Charlotte's Web— to a handful of licensed facilities. These laws have drawn both praise and criticism from various groups, as many feel they stop well short of where we eventually need to be in regards to Medical Marijuana Oil and Medical Cannabis, limiting the use to only a handful of patients that are on a very short list of approved conditions and in some cases, exclusively for Epilepsy.
Final thoughts: Hemp oil and hemp derived CBD oil is legal in all fifty states, but there certainly is a stigma to it. Because of that it can be very hard to find reliable information to educate yourself with. This is a great dietary supplement and may help decrease inflammation, improve skin, help with mild pain, etc. If you have severe pain, hemp derived CBD oil may be what you need.
The fatty acids contained in CBD hemp oil have an important vasodilation property and so clots are prevented from developing within the blood vessels. This is how another beneficial feature is added to this oil and it deals with supporting the skin’s layers to develop cellulitis. So why not give CBD hemp oil a try? You might find a perfect health ally in it. https://hlbenefits.com/cbd-pure-reviews/
When the researchers evaluated the effects of PET compared with THC on inflammation pathways in mouse brains, they finally found a difference. Although PET’s psychoactive effects were less potent, it reduced certain molecules associated with inflammation, says study author Michael Schafroth, currently a postdoctoral researcher at The Scripps Research Institute.
In June 2018, the FDA approved the drug Epidiolex, an oral preparation of pure CBD for treatment of two rare and severe forms of epilepsy in children. The drug is made by the GW Pharmaceutical Company and was tested in three randomized, double-blind, placebo-controlled clinical trials, including 516 patients. It was found to be effective in reducing the frequency of seizures.

Ananda Hemp is a tempting brand to say the least. They source their seeds from the largest hemp seed bank in the United States and have generational farmers grow their products. Plus, they offer excellent customer service with their products. However, I was disappointed that they had only two concentrations of tinctures available, one amounting to 200 mg and other being 600 mg.
When privacy isn’t a requirement, outdoor cannabis grows can provide many advantages over indoor operations. Sunlight is the single most important factor for successful outdoor marijuana growing. It’s important to choose a plot with total sunshine throughout the day. Therefore, cannabis growers in the northern hemisphere will want plots with southern exposure, exposing marijuana plants to the sun’s arc across the sky.
Marijuana or marihuana (herbal cannabis),[166] consists of the dried flowers and subtending leaves and stems of the female Cannabis plant.[167][168][169][170] This is the most widely consumed form,[170] containing 3% to 20% THC,[171] with reports of up-to 33% THC.[172] This is the stock material from which all other preparations are derived. Although herbal cannabis and industrial hemp derive from the same species and contain the psychoactive component (THC), they are distinct strains with unique biochemical compositions and uses. Hemp has lower concentrations of THC and higher concentrations of CBD, which decreases the psychoactive effects[173][174]
Cannabidiol (CBD) is a naturally occurring compound found in the resinous flower of cannabis, a plant with a rich history as a medicine going back thousands of years. Today the therapeutic properties of CBD are being tested and confirmed by scientists and doctors around the world. A safe, non-addictive substance, CBD is one of more than a hundred “phytocannabinoids,” which are unique to cannabis and endow the plant with its robust therapeutic profile.
Although marijuana smoke contains a number of carcinogens findings from a limited number of well-designed studies do not suggest an increased risk for the development of either lung or upper airway cancer from light or moderate use. However, the evidence is mixed when it comes to the carcinogenic risks of heavy, long-term marijuana users, according to this study.
I have spent the last year + researching over 200 CBD companies and their products. I learned how the CBD is extracted, the difference between IH (Industrial Hemp) and THC producing cannabis that is harvested early, so that is is given the legal term Hemp, but technically it is the marijuana plant, etc. First, I chose not to take CBD orally, because of how the body breaks down CBD, when you digest it, it goes through the liver first, meaning less than 20% of what you take ends up in your body. Very expensive!! With vaping CBD oil about 70% makes it right into your bloodstream. With the CBD wax/shatter/dab, it is the same. So I stopped the oral route altogether. If you would oral or vape (inhaling vapor, no combustion), you want to look to see or email the company to ask how they extract the CND, and ask if they use CBD frown in the US. I highly suggest CBD frown in the US! The old law had people growing it overseas, and shipping it here to be extracted. Make sure no solvents were used to extract the CBD, like Butane. Whatever they tell you about how they extract it, look it up! This is a MUST! The most common ways to extract are via CO2 extraction using cold temperatures sometimes called subcritical or supercritical temperatures, same with ethanol extraction, there is no solvent in that either. Please research online both methods. There are a couple of other methods, one comes to mind, but it does not stay fresh long, and I cannot recall the name, I have not found any products which use that method, which is why I cannot name it. After making sure it is not done with anything dangerous, you want to make sure they have batch lab reports that check for heavy metals, mold, and how much CBD,CBG,CBC, etc is in the product. CBD, Cannabidiol is the most common Cannabinoid found in the marijuana or hemp plant. Did you know that IH contains a very small amount of THC? it is at or under.3%, so it is low, but it does help the CBD work.

So is CBD legal? If we’re talking about hemp-derived CBD, then the answer is yes. Now, the keyword here is “hemp-derived.” Because CBD from hemp has no psychoactive effects, the purchase, sales, or possession of hemp CBD products are completely legal in all 50 States. Because hemp is sometimes confused with the marijuana plant, there is still some stigma towards hemp-derived CBD, but from a legal perspective, hemp-derived CBD is completely legal and enjoys the rights of any other legal product.


This cream is magical. I suffer from knee problems, back problems, arthritis everywhere, the list goes on. I apply this cream where needed when needed, and not only does it bring relief, it buys me more time of not needing the relief…..sometimes a week will go buy before i need to apply it again. Better than any holistic cream/salve, and prescription cream I’ve ever had.
If you act today, you can see results and save money with CBD Pain Cream. Because, right now, CBD Pain Cream is offering a discount to all first-time customers. You can get your coupon in your email if you act today. Then, you get to save some money on this life changing solution. If you’re tired of being dependent on expensive and dangerous prescription drugs, this is for you. Don’t let pain hold you back anymore! Your life is worth more than that. Get on with your life and live pain-free with your CBD Pain Cream order. It’s going to make life so much easier.
Hemp Bombs is a dedicated CBD brand that strives to provide you with products that will help and improve your overall wellness. We manufacture and package all our CBD products in-house, which gives us a competitive advantage. In-house manufacturing lets us maintain quality control over our products from the factory floor to your door. We also verify the purity of our products through third-party lab tests. We want to guarantee that you are receiving a pure certified product that is beneficial to your health. Our outstanding and knowledgeable customer service also complements hemp Bombs quality control. When looking after your health, make sure to choose Hemp Bombs, the CBD brand that puts you first.
     CBD content in Hemp oil, when extracted from the proper strains, can be very high as Hemp plants are now the very strains that are being used to breed high CBD levels back into Cannabis after years of selective recreational breeding for high THC values. Well known strains such Charlotte's Web are hybrids that were selected from crosses with High CBD Hemp varietals and those Hemp genetics are what account for the new High CBD Strains of Marijuana and commercial Hemp that have and are being developed.

Because it takes a significantly larger amount of hemp stalks to produce hemp oil, there is an increased risk of contamination of toxins contained within the plant. This is a result of hemp's strong bio-accumulator properties, where it pulls toxins from the soil it grows in. Many hemp oils are also known to lack the full spectrum of terpenes and other cannabinoids that are believed to act synergistically with the CBD, meaning that consumers receive less of a benefit. That being said, there are some brands that test rigorously to make sure that the CBD content, as well as the terpenes and other cannabinoids, are up to par. It's a good sign if they offer to provide a certificate of analysis, which will tell you what kind of compounds are in the hemp oil and in what concentrations
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Specific city and county laws have been enacted to regulate how citizens and tourists may possess and consume marijuana. Penalties exist for driving while under the influence of marijuana. Someone driving under the influence of marijuana is considered impaired in both Colorado and Washington when five nanograms per milliliter (ng/mL) of blood or more of active THC is detected.
Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.
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