Unlike other CBD oils, PureKana really does excel in CBD oil extractions due to their unique CO2 extraction process which provides a near 99% pure CBD oil. PureKana Natural CBD Oil is an unflavored, dietary and nutritional supplement for increased health and vitality. It is extremely effective in treating chronic pain, inflammation, swelling, anxiety and sleep disorders.
In 2014, the South Carolina legislature passed S 1035/H 4803, also known as “Julian’s Law.” The law creates an exemption for the possession and use of CBD from the criminal definition of marijuana in limited circumstances. Only patients with severe forms of seizure disorders are eligible for legal protections after the patient obtains a recommendation for CBD oil from a physician.
Carbon dioxide is passed through the plant material at a very specific temperature and pressure. Carbon dioxide, which is normally a gas at (or above) room temperature, can be pressurized until it becomes so dense that it takes on some of the properties of a liquid while still maintaining the fluid dynamics of a gas. In this state, CO2 is known as a supercritical fluid.
New companies are already popping up, making products from Whole Plant extracts taken from high quality domestic or European Hemp plants with more complete Cannabinoid profiles and offering concentrations of CBD in their extracts similar to what is obtainable from strains such as Charlotte's Web. Charlotte's Web itself has recently been reclassified from Marijuana by the state of CO as a Hemp variety (story here) which will allow for the sales of Hemp based finishing products derived from it in all U.S. states, the same as other legal Hemp based CBD nutritional supplements that are currently being sold.
About 49% of the weight of hempseed is an edible oil[7] that contains 76% as essential fatty acids; i.e., linoleic acid, omega-6 (LA, 54%), alpha-linolenic acid, omega-3 (ALA, 17%), in addition to gamma-linolenic acid (GLA, 3%), monounsaturated fat (5% to 11%), and stearidonic acid (2%).[8] Hemp seed oil contains 5% to 7% saturated fat.[7][8] In common with other oils, hempseed oil provides 9 kcal/g. Compared with other culinary oils it is low in saturated fatty acids.[8]
When formulating a CBD regimen for a specific disease or illness (like chronic or neurological pain), it’s important to understand that CBD should be used regularly for maximum relief. Meaning it should be used as a preventative first – it can also be used to manage acute flare ups, but the preventative maintenance is most important! Think about it like any other dietary supplement, you want to establish a baseline concentration in your system.
In late 2017, researchers with the University of Guelph in Canada published the first-ever study to document the ideal growing conditions for cannabis. Using liquid organic fertilizer with a PKN ratio of 1.3P–1.7K-4.0N, the experiment tested five increasing rates of fertilization. They also tested two coir-based soil-less growing media, or “substrates.”
Despite the many states that have legalized some or all forms of marijuana, federally the U.S. Drug Enforcement Administration (DEA) continues to classify CBD as a Schedule I drug. Schedule I drugs are defined by the DEA as "drugs with no currently accepted medical use and a high potential for abuse." This is how not just CBD, but the entire cannabis plant is classified.
Children and young teens start using marijuana for many reasons. Curiosity and the desire to fit into a social group are common motivating factors. Young people who have already begun to smoke cigarettes and/or use alcohol are at high risk for marijuana use. They may have family problems or a network of friends who use drugs and urge them to do the same (peer pressure).

While most supplements have a single recommended dose, CBD is different. The amount of CBD you take depends on your doctor’s recommendations and your own research into how CBD will work for your unique needs. In general, it’s smart to start with a medium dose of CBD. This way, you can increase or decrease the dose as needed. In addition, it’s recommended to start with one half ML (half a dropper) of CBD oil, because you can always take more if needed.


A co-worker tried to get me to use this a few times but I was reluctant to use a marijuana product. She told me that it wasnt and I did try it. I really liked it even tho it seemed no different than other pain rub stuff. It worked really well, so I went online to buy some and right now its on back order. ( it figures) So I patiently await its availability. You should have a waiting list for back order stuff.
Users of CBD have found that CBD products help them with a wide range of health problems such as insomnia, physical pain, and anxiety. CBD has also been studied for its anti-seizure properties and its ability to combat brain damage caused by opioid addiction. Currently, the Food and Drug Administration (FDA) is in the process of approving a CBD-based epilepsy medication which will make it the first cannabis-derived prescription medication in the United States.
CBD Oil can also contain ZERO amount of THC. If this were coffee, it’s all in the grind. It still is, figuratively, for hemp CBD oil. We developed a product from listening to our customers that needed 100% certainty their oil didn’t contain trace amounts of THC. Like who? First responders, athletes, military personnel, or anyone that wants 100% confidence they’re consuming only CBD. Read more about it here.
The genus Cannabis was formerly placed in the nettle (Urticaceae) or mulberry (Moraceae) family, and later, along with the genus Humulus (hops), in a separate family, the hemp family (Cannabaceae sensu stricto).[45] Recent phylogenetic studies based on cpDNA restriction site analysis and gene sequencing strongly suggest that the Cannabaceae sensu stricto arose from within the former family Celtidaceae, and that the two families should be merged to form a single monophyletic family, the Cannabaceae sensu lato.[46][47]

Chronic pain leads to a feeling of despair and hopelessness. One wonders if the pain will ever end? Will I ever get my life back? An unexpected finding during our study was that our patients were coming back to us saying they were hopeful. Instead of their glass being half empty, it was now half full. Hope is powerful. When you have hope, your mind starts to work for you instead of against you. You start to imagine that things can be different. You find the motivation to get off the couch and get busy living instead of waiting to die. This feeling of hope inspired these patients to start engaging in activities we had encouraged them to do for years, like doing yoga, eating healthier, losing weight and moving more.
Cannabis, a drug prepared from the plant Cannabis sativa (including marijuana, resin, and “skunk”), is used widely throughout the world and is especially popular in North America, Western Europe, West and Central Africa, and Oceania (United Nations Office on Drugs and Crime, 2009). Several studies within the past decade have investigated the effect of continuous use of cannabis on psychotic illnesses, specifically schizophrenia. Zammit, Allebeck, Andreasson, Lundberg, and Lewis (2002) in Sweden found that those who smoked cannabis had a twofold increased risk of developing schizophrenia within 15 years. In addition, the researchers also found a dose–response relationship; subjects who used cannabis more heavily (over 50 reported occasions) were six times as likely to develop schizophrenia compared to those who did not use cannabis at all.
Holcomb said after enacting the bill, “I’m grateful for the General Assembly’s hard work to bring me a bill to address the needs expressed by our citizens.” As of now, there is no restriction on the sale of CBD oil except it should not have more than 0.3 percent of THC (Tetrahydrocannabinol). THC is the compound that is associated with producing a high.
Physiological manifestations like stress, and poor diet may negatively impact other systems in the body via specific cellular processes. Nutrition plays an important role in preserving various systemic and metabolic functions by supplying the appropriate dietary needs to the body system. The nutrient signaling pathways are coupled to cellular processes, and the cross-talk between the two is critical in maintaining a well-balanced systemic function of the body. The systemic imbalance may occur under circumstances such as stress, and fatigue, which may trigger inflammatory responses in the body3 and inflammation may cause unwanted health conditions. It has been shown that various dietary components may support key resolution pathways to inflammation, energy balance and metabolism via the ECS.4,5,6,7,8 Nutrients that may support healthy inflammatory response include omega-3 fatty acids, and antioxidants, from a whole food matrix in the form of phytonutrients.2,9
Other “minor phytocannabinoids” in cannabis may also contribute relevant activity (McPartland and Russo 2001). Cannabichromene (CBC) is the third most prevalent cannabinoid in cannabis, and is also anti-inflammatory (Wirth et al 1980), and analgesic, if weaker than THC (Davis and Hatoum 1983). Cannabigerol (CBG) displays sub-micromolar affinity for CB1 and CB2 (Gauson et al 2007). It also exhibits GABA uptake inhibition to a greater extent than THC or CBD (Banerjee et al 1975), suggesting possible utilization as a muscle relaxant in spasticity. Furthermore, CBG has more potent analgesic, anti-erythema and lipooxygenase blocking activity than THC (Evans 1991), mechanisms that merit further investigation. It requires emphasis that drug stains of North American (ElSohly et al 2000; Mehmedic et al 2005), and European (King et al 2005) cannabis display relatively high concentrations of THC, but are virtually lacking in CBD or other phytocannabinoid content.
It’s also important to select CBD oil products based on your concentration preferences. Some forms of CBD oil – such as vapors and tinctures – normally have higher-than-average concentrations, whereas sprays and topicals tend to have lower concentrations. Remember: higher concentration means more pronounced effects, but not necessarily mean higher quality.
First… hemp, cannabis, marijuana (slang term)… they’re from the exact same plant species – Cannabis sativa. It’s common to mistake hemp and cannabis unless you know why they’re different. The easiest way to tell? If it’s under .3% THC content then it’s hemp and is classified as legal for academic and educational purposes, according to federal law. What is commonly referred to as cannabis (or medical marijuana) contains THC levels above .3% and can extend into levels between 15-30% THC. Remember, THC (tetrahydrocannabinol) is the psychoactive component of cannabis. Without these higher THC levels, there are no psychoactive effects for you.

     CBD content in Hemp oil, when extracted from the proper strains, can be very high as Hemp plants are now the very strains that are being used to breed high CBD levels back into Cannabis after years of selective recreational breeding for high THC values. Well known strains such Charlotte's Web are hybrids that were selected from crosses with High CBD Hemp varietals and those Hemp genetics are what account for the new High CBD Strains of Marijuana and commercial Hemp that have and are being developed.
Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.

     CBD content in Hemp oil, when extracted from the proper strains, can be very high as Hemp plants are now the very strains that are being used to breed high CBD levels back into Cannabis after years of selective recreational breeding for high THC values. Well known strains such Charlotte's Web are hybrids that were selected from crosses with High CBD Hemp varietals and those Hemp genetics are what account for the new High CBD Strains of Marijuana and commercial Hemp that have and are being developed.


A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders.[68][69] Since then, 16 states have passed laws to allow the use of CBD products with a doctor's recommendation (instead of a prescription) for treatment of certain medical conditions.[70] This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content.[70] Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.[70]
Professors William Emboden, Loran Anderson, and Harvard botanist Richard E. Schultes and coworkers also conducted taxonomic studies of Cannabis in the 1970s, and concluded that stable morphological differences exist that support recognition of at least three species, C. sativa, C. indica, and C. ruderalis.[68][69][70][71] For Schultes, this was a reversal of his previous interpretation that Cannabis is monotypic, with only a single species.[72] According to Schultes' and Anderson's descriptions, C. sativa is tall and laxly branched with relatively narrow leaflets, C. indica is shorter, conical in shape, and has relatively wide leaflets, and C. ruderalis is short, branchless, and grows wild in Central Asia. This taxonomic interpretation was embraced by Cannabis aficionados who commonly distinguish narrow-leafed "sativa" strains from wide-leafed "indica" strains.[73] 

Several CBD manufacturers would not speak on the record for fear of inviting federal retaliation, but said they’ve recently had trouble selling their products to non-cannabis retail stores. In January, the Seattle Central Co-op pulled CBD products from its shelves in reaction to the DEA rule. Meanwhile, CBD remains available online and at many retail health stores across the nation.
Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.
If your intention is to help treat chronic pain, then you may want to start out with a lower dose, and then proceed from there. If you notice effective results, you can downsize the dose, or likewise you can always up the dose until positive results are achieved. The key is to only increase your dosage in small increments so that you are able to pinpoint exactly how much CBD oil it takes to treat your condition. Be advised, though, that you should not exceed the recommended daily doses that are listed on the bottle and you should consult with a physician.
The rosemary acts as a natural antioxidant preservative. It also supplies terpenoids, including camphene, pinene, and limonene, that support a healthy inflammatory response and promote relaxation.* Hops is a very close cousin of hemp and many of the compounds in hops are complementary to those in hemp. The hops in Hemp Oil + provides a source of the terpenoids humulon and lupulon that are synergistic with the phytocannabinoids in support of the ECS.*

After revisions to cannabis scheduling in the UK, the government moved cannabis back from a class C to a class B drug. A purported reason was the appearance of high potency cannabis. They believe skunk accounts for between 70 and 80% of samples seized by police[162] (despite the fact that skunk can sometimes be incorrectly mistaken for all types of herbal cannabis).[163][164] Extracts such as hashish and hash oil typically contain more THC than high potency cannabis flowers.[165]


A. We understand that parents are trying to find treatments for their children’s medical conditions. However, the use of untested drugs can have unpredictable and unintended consequences. Caregivers and patients can be confident that FDA-approved drugs have been carefully evaluated for safety, efficacy, and quality, and are monitored by the FDA once they are on the market. The FDA continues to support sound, scientifically-based research into the medicinal uses of drug products containing marijuana or marijuana constituents, and will continue to work with companies interested in bringing safe, effective, and quality products to market.
In some areas where cannabis use had been historically tolerated, new restrictions were instituted, such as the closing of cannabis coffee shops near the borders of the Netherlands,[221] and closing of coffee shops near secondary schools in the Netherlands.[222] In Copenhagen, Denmark in 2014, mayor Frank Jensen discussed possibilities for the city to legalize cannabis production and commerce.[223]
Another common side effect that hemp oil can cause in supplement users involves the cardiac system and bloodstream. As the PeaceHealth website states, hemp oil products can directly affect the anticoagulant properties of platelets within the blood, often inhibiting their very production. As a result, patients who are currently being treated for a blood clotting deficiency or other cardiac medical condition are strongly advised to stay away from hemp oil supplements of any kind due to possible symptom complications.

While CBD can be extracted from non-hemp varieties of the plant, hemp-derived CBD is less restricted by the government because of its inherently low levels of THC. CBD from hemp is legal for sale in most US states, while CBD products derived from non-hemp varieties can contain noticeable amounts of THC, and are therefore subject to stricter laws and regulations.
Cannabis is frequently used among Sufis[132] – the mystical interpretation of Islam that exerts strong influence over local Muslim practices in Bangladesh, India, Indonesia, Turkey, and Pakistan. Cannabis preparations are frequently used at Sufi festivals in those countries.[132] Pakistan's Shrine of Lal Shahbaz Qalandar in Sindh province is particularly renowned for the widespread use of cannabis at the shrine's celebrations, especially its annual Urs festival and Thursday evening dhamaal sessions - or meditative dancing sessions.[133][134]
Perhaps the biggest concern for anybody with a job or kids or other responsibilities is whether CBD will induce psychoactive effects. While it’s true that CBD comes from cannabis plants, it does not cause any high. The two main compounds in cannabis are CBD and THC; and they are completely different in the effects they generate in the body. THC makes you high, but CBD stabilizes cognitive and neurological functions.
CBD, short for cannabidiol, is a compound found in cannabis that has gained prominence in recent years for its therapeutic properties. Cannabis advocates have hailed the cannabinoid for its promise in combating seizures, anxiety and myriad other ailments. CBD is "the new ‘it’ drug," according to The Washington Post. It’s a "rapidly rising star for its capacity to deliver mental and physical benefits," according to Quartz.
Hashish (also spelled hasheesh, hashisha, or simply hash) is a concentrated resin cake or ball produced from pressed kief, the detached trichomes and fine material that falls off cannabis flowers and leaves.[178] or from scraping the resin from the surface of the plants and rolling it into balls. It varies in color from black to golden brown depending upon purity and variety of cultivar it was obtained from.[179] It can be consumed orally or smoked, and is also vaporised, or 'vaped'.[180] The term "rosin hash" refers to a high quality solventless product obtained through heat and pressure.[181]
Cannabis is known to aid relaxation, which makes it a popular treatment for social anxiety – however due to the THC content in cannabis, it can actually trigger more intense feelings of paranoia and anxiety. CBD on the other hand, has the opposite effect, helping to calm down the nerves and keep you grounded. Anxiety disorders and other feelings of irrational fear can be overwhelming especially if you find yourself in unfamiliar environments, however CBD can be used effectively to generate calmness and peacefulness, and without the addictive component of anti-anxiety medication like Benzos or Xanax.
^ Hayakawa K, Mishima K, Hazekawa M, Sano K, Irie K, Orito K, Egawa T, Kitamura Y, Uchida N, Nishimura R, Egashira N, Iwasaki K, Fujiwara M (January 2008). "Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB(1) receptor-dependent mechanism". Brain Research. 1188: 157–64. doi:10.1016/j.brainres.2007.09.090. PMID 18021759.
While CBD oil does a fine job of reducing stress, anxiety and the effects of chronic pain, it doesn’t have the same localized effect as CBD cream for pain. For example, if you have severe shoulder pain, CBD cream is a much better option than oil because it will get to work on that area immediately. The CBD in the topical combines with the CB2 receptors in our skin. As it doesn’t reach the bloodstream, it is best used for localized pain since it doesn’t offer full-body pain relief.
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