A limited number of studies have examined the effects of cannabis smoking on the respiratory system. Chronic heavy marijuana smoking is associated with coughing, production of sputum, wheezing, and other symptoms of chronic bronchitis. The available evidence does not support a causal relationship between cannabis use and chronic obstructive pulmonary disease. Short-term use of cannabis is associated with bronchodilation. Other side effects of cannabis use include cannabinoid hyperemesis syndrome.
Since marijuana is illegal on a federal level, but legal on a state-by-state basis, growers and cannabis businesses cannot legally transport cannabis products across state lines. Some companies that make CBD products — usually supplied in the form of lotion, oils, and pills — have done so anyway, based on the claim that CBD derived from hemp can be classified as botanical extract and a dietary supplement. But over the past few years, the FDA has issued numerous “cease and desist” letters to companies produce cannabis products warning them not to make health-related CBD claims and making clear that it does not consider CBD a dietary supplement.
The rosemary acts as a natural antioxidant preservative. It also supplies terpenoids, including camphene, pinene, and limonene, that support a healthy inflammatory response and promote relaxation.* Hops is a very close cousin of hemp and many of the compounds in hops are complementary to those in hemp. The hops in Hemp Oil + provides a source of the terpenoids humulon and lupulon that are synergistic with the phytocannabinoids in support of the ECS.*
The relationship between THC and CBD is complex, but in short, CBD appears to minimize some of THC’s undesirable effects, such as paranoia, heart palpitations, and impaired thinking. Compared with THC in isolation, or its synthetic cousins such as Marinol, the combination of THC and CBD has much greater therapeutic value to patients. This phenomenon of cannabis-derived molecules working better together than they do in isolation is commonly referred to as the entourage effect.
There have been a number of studies investigating the conceivable part of CBD oil in vanquishing pain of all proportions, be it menstrual cramps or pain of a chronic magnitude. The Journal of Experimental medicine speaks about the utilization of CBD oil for suppressing neuropathic pain in rodents. In spite of the fact that such studies are yet to be replicated with human beings, CBD oil is a good tolerance-builder, an agent that enhances the physique’s ability to cope with and be resilient to pain.
CBD was first discovered in 1940 by Roger Adams, a prominent organic chemist at the University of Illinois. Shortly thereafter, other scientists began testing isolated cannabinoids on lab animals; notably, Walter S. Loewe ran trials on mice and rabbits with the cannabinoids THC, CBD and CBN. He found that CBD produced no observable effects in the animals’ behavior while THC caused, what he called, a “central excitant action” in rabbits. Despite science’s movement forward, scientists were completely unaware of the cannabinoids’ chemical structure, so no one could tell which specific compound resulted in which effect.
‘A good pointer of quality is that the manufacturer will be a member of the Cannabis Trades Association UK, an organisation created to ensure legal and ethical CBD trading standards, says Dr Brewer. ‘Only companies that meet high quality standards can carry its seal of approval such as Healthspan’s range of CBD Oil products, for whom I act as Medical Director.’
The CBD oil we offer has a couple different applications. You can hold a sublingual dose under the tongue for 30-60 seconds (recommended for fastest absorption), apply the oil topically to your skin (can be applied directly to a problem area or mixed with your favorite moisturizer), or blend the oil in a health-conscious smoothie. We will include further dosing instructions with the product.
Subsequent studies were carried out in different countries, which confirmed the results found in the Zammit et al. (2002) study, showing that those clinically dependent on cannabis by 18 years of age had an increased risk of later developing psychotic symptoms (Fergusson, Horwood, & Swain-Campbell, 2003). Cannabis users were also more likely to develop schizophreniform disorder (Arseneault et al., 2002), and the dose–response relationship found in the first study was confirmed (Henquet et al., 2005).
Chronic pain leads to a feeling of despair and hopelessness. One wonders if the pain will ever end? Will I ever get my life back? An unexpected finding during our study was that our patients were coming back to us saying they were hopeful. Instead of their glass being half empty, it was now half full. Hope is powerful. When you have hope, your mind starts to work for you instead of against you. You start to imagine that things can be different. You find the motivation to get off the couch and get busy living instead of waiting to die. This feeling of hope inspired these patients to start engaging in activities we had encouraged them to do for years, like doing yoga, eating healthier, losing weight and moving more.
Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.
Amendment 64 granted Colorado citizens the use and regulation of marijuana. Passed on November 6, 2012, it included a declaration industrial hemp should be regulated separately from marijuana and that the Colorado General Assembly is “to enact legislation governing the cultivation, processing, and sale of industrial hemp.” Soon after Amendment 64 went into effect, Colorado became the first state to contain certified hemp seed – designated as containing less than .3% THC – as well as free of weeds and disease.
It’s easy to see why vaping has become such a popular method for consuming marijuana. The method is remarkably discrete and produces none of the telltale “weed smells” that often betray cannabis users. Vape pens and other hand-held devices are portable and convenient. They’re free of many of the harsh marijuana plant compounds that can harm your lung health, like tars. And companies are getting better at crafting high-quality, flavorful vape cartridges with a wide array of cannabinoid profiles.
Whether the drug and non-drug, cultivated and wild types of Cannabis constitute a single, highly variable species, or the genus is polytypic with more than one species, has been a subject of debate for well over two centuries. This is a contentious issue because there is no universally accepted definition of a species. One widely applied criterion for species recognition is that species are "groups of actually or potentially interbreeding natural populations which are reproductively isolated from other such groups." Populations that are physiologically capable of interbreeding, but morphologically or genetically divergent and isolated by geography or ecology, are sometimes considered to be separate species. Physiological barriers to reproduction are not known to occur within Cannabis, and plants from widely divergent sources are interfertile. However, physical barriers to gene exchange (such as the Himalayan mountain range) might have enabled Cannabis gene pools to diverge before the onset of human intervention, resulting in speciation. It remains controversial whether sufficient morphological and genetic divergence occurs within the genus as a result of geographical or ecological isolation to justify recognition of more than one species.
Though clinical and anecdotal evidence suggests CBD’s benefits in managing different conditions, it became most famous for treating a rare and debilitating form of pediatric epilepsy. Dravet’s Syndrome is notoriously resistant to current approved treatment methods. Sufferers are plagued by seizures, often up to hundreds a day, that worsen as they age and can be life-threatening. Currently, treatment methods include having the child wear an eyepatch, specialized diets, and brain surgery, but all have mixed success rates.
I appreciate the Fast delivery and thorough packaging. Had my wife try this last night and she compared it to a different brand hemp product she has been using. She likes your product better, especially because it does not have an awful taste like the other product. it provided some pain relief for her RA and fibro but the initial dosage may not have been enough drops. She tried about 20 droplets and was able to sleep through the night.
In June 2018, the FDA approved the drug Epidiolex, an oral preparation of pure CBD for treatment of two rare and severe forms of epilepsy in children. The drug is made by the GW Pharmaceutical Company and was tested in three randomized, double-blind, placebo-controlled clinical trials, including 516 patients. It was found to be effective in reducing the frequency of seizures.
NIDA provides research-grade marijuana for scientific study. The agency is responsible for overseeing the cultivation of marijuana for medical research and has contracted with the University of Mississippi to grow marijuana for research at a secure facility. Marijuana of varying potencies and compositions is available. DEA also may allow additional growers to register with the DEA to produce and distribute marijuana for research purposes.
Truth be told, one of the biggest draws to using CBD oil for pain has been the fact that it has little distinguishable side-effects or contraindications with other medications. In fact, in a massive report that was published by the World Health Organization during last year’s 2017 Expert Committee on Drug Dependence, it was (finally) declared to the world that CBD is a “safe, well tolerated [compound, which] is not associated with any significant adverse public health effects.”