This guide is an introduction to anyone looking to inform themselves about the reality of cannabis. It covers basic information about the marijuana plant, cannabis preparations, and the crucial elements of plant anatomy and science. This guide to marijuana also gives an overview of the most popular medical and recreational uses of cannabis. It offers a survey of the most important medical cannabis research while highlighting emerging trends in the legal cannabis market. The guide also introduces those new to cannabis to the many ways to consume marijuana, and much more.
As the PeaceHealth website suggests, hemp oil derives from a plant that contains high levels of the neurological chemical THC. This chemical can cause hallucinations, euphoria or high anxiety in supplement users when taken on a regular basis. As such, hemp oil supplements can cause similar effects in some patients using the herb for the treatment of any disorder. It is recommended that supplement users not take hemp oil products prior to operating machinery or driving due to the risk of these hallucinogenic properties. This is especially true to individuals who are overly-sensitive to THC, which can be determined by visiting your medical doctor for more information.
Moreover, scientists at the Cajal Institute showed promising results in regards to CBD and Multiple Sclerosis. They used animal models and cell cultures to find that CBD reversed inflammatory responses; within only ten days, mice that were used in the study had superior motor skills and showed progression in their condition. To date, there have been well over 20,000 published scientific articles on cannabinoids and their related effects on all sorts of medical ailments.
California’s legalization spurred Dr. Geoffrey Guy and Dr. Brian Whittle to found GW Pharmaceuticals, a company that would utilize clinical trials to unpack various cannabinoid formulations as potential therapies with the overriding focus of developing what would later be known as Sativex (Nabiximols). This oral mucosal spray was made up of CBD and THC in a 1:1 ratio and successfully combated neuropathic pain, spasticity, overactive bladder, and symptoms of multiple sclerosis.
The legal problems occur once the extracts contain higher percentages of THC, or when they’re made from cannabis plants that are no longer considered “hemp” (so basically high THC plants). Products with these extracts might be in violation of the United States Controlled Substances Act (US CSA). This is when laws regarding specific states or countries will apply.
We have been using cannabis oil with a 1:1 CBD/THC ratio from “AnnCannMed” in treating my husband with pancreatic cancer with a lot of improvement since 4 weeks and the product is working in a miraculous way beyond our expectations. The medication is working with super proof. We recommend you visit AnnCannMed for your health prescriptions and medical purchases and feel support talking to licensed physicians
LEGAL NOTICES: Care By Design products have not been evaluated by the Food and Drug Administration (FDA). This information is not intended to diagnose, treat or cure any disease. This information should not be interpreted as medical advice or treatment. You should consult your physician or other health care professional before starting any medication or supplements. Further, Care By Design does not manufacture, sell or distribute any products that are in violation of California State Law.

The author of a Harvard-led systematic review of 28 studies examining the efficacy of exo-cannabinoids (cannabinoids formed outside of the body, i.e. from the plant or synthetically made) to treat pain and other medical issues concluded, “the use of marijuana for chronic pain, neuropathic pain, and spasticity due to multiple sclerosis is supported by high-quality evidence.”
Before thing’s started getting out of hand with chronic pain really settling in, I used CBD oil for about a year. I kept waiting and waiting to feel better. Until I just couldn’t take the pain any longer. Than I tried Herion. I did not like that at all, pluse was a little frightened of it. Than I finally asked for pain meds. I just had to find the right dosage. Was doing very good with it. Than I was cut cut back to guidelines, now not so good again. So now what? Their he’ll bent on making Kratom illegals. They just want us all to suffer and die, I’m convinced.
     While these CDB laws are well intentioned and make certain types of cannabis oil legal in certain states, many of them are extremely exclusive as to what illnesses may qualify patients for use, and limit production of the plant—in most cases Charlotte's Web— to a handful of licensed facilities. These laws have drawn both praise and criticism from various groups, as many feel they stop well short of where we eventually need to be in regards to Medical Marijuana Oil and Medical Cannabis, limiting the use to only a handful of patients that are on a very short list of approved conditions and in some cases, exclusively for Epilepsy.
CBD (cannabidiol) oil is a popular product for everything from pain control to promoting sleep. However, with the rise of CBD comes the concern about failing a drug test due to detection of CBD oil. News stories are emerging across the country involving famous sports players, employees of companies, and others who have gotten positive drug screening results for the presence of THC—the psychoactive component of marijuana—even though CBD oil is said to be THC-free. 
REM behavior disorder: REM behavior disorder (RBD) is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep. For many, RBD is a symptom of a larger, more serious condition or disorder, such as Alzheimer’s disease or PTSD. CBD oil minimizes the symptoms of RBD, and also alleviates the anxiety and painful symptoms that often accompany disorders that lead to RBD.
CBD e-liquids are made for vaporizers or electronic cigarettes. Usually, hemp extract or pure CBD is mixed with a classic e-liquid base called PG/VG. The e-liquids are then inserted into a cartridge or atomizer for an electronic cigarette. You may see the CBD vape oil used interchangeably with CBD e-liquids, so keep that in mind and don’t vape your regular CBD-rich oil unless you want a not so enjoyable experience.
The legality of CBD in the US varies from state to state, but at the federal level, CBD is mysteriously classified as a Schedule I drug despite its sourcing. According to the federal government, Schedule I drugs are substances or chemicals with no currently accepted medical use and a high potential for abuse. Other Schedule I drugs include heroin, LSD, marijuana, and ecstasy. However, CBD can be purchased as a dietary supplement throughout the country despite the FDA’s official stance that CBD isn’t a supplement. The landscape of CBD legality in the US is exactly as confusing as it reads; that squirrely, perplexing itch at the back of your brain is cognitive dissonance, and it’s an entirely normal reaction.
CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.
CBD oil alleviates physical pain and anxiety – both of which can have a negative impact on sleep. Additionally, CBD oil can actually prolong sleep for some, leading to more rest from night to night. Most medical experts agree that marijuana is not particularly beneficial for individuals with medical conditions and/or mental health disorders, as the THC can increase their symptoms; this makes CBD oil a good alternative option for people with the following sleep disorders and medical conditions.
The FDA’s refusal to allow companies to market CBD as a dietary supplement is based on the fact that federal classification as a dietary supplement requires that a substance has not been authorized for investigation as a new drug or medicine. Since Epidiolex has been studied in clinical trials by GW Pharmaceuticals going back several years now and was granted orphan drug status by the FDA in 2013, CBD cannot therefore be classified as a dietary supplement. Or so the FDA says. But cannabis companies are arguing that they started marketing CBD as a dietary supplement before there were any drug trials involving CBD, such that they should still be allowed to claim dietary supplement status for their products. Thus far however, the FDA isn’t budging on this issue.  

Rather than being a downside, the ability of CBD cream to focus on one area means it is perfect for use on joint pains. When you rub CBD cream on your joints, it uses its anti-inflammatory properties to provide rapid and long-lasting pain relief in a specific area. As a result, you benefit from a soothing sensation on swollen joints which should lead to improved mobility. As well as being the ideal solution for people who have arthritis, CBD cream helps with the following skin conditions:
Depression? Arthritis? Inflammation contributes to pain, stiffness, and poor health over time. Many individuals opt for CBD to control inflammation. However, THC has a part to play as well. Research suggests that, in some instances, the cannabis compound can decrease the production of cytokine and chemokine compounds in the body. Cytokine and chemokines are immune compounds that trigger inflammation. Additional pre-clinical research suggests that it may be able to decrease inflammation by suppressing genes related to inflammatory response. I believe people deserve access to all parts of the cannabis plant! Together, we can spread the cannabis education not DEA lies! Just as they have done opiates! Also, it’s ridiculous to wage war between the two! Have pain patients saying medical marijuana doesn’t work etc and others saying opiates are bad. There should be access to both – whatever works for someone! I never used marijuana until forced off my opiates cold turkey in cancer recurrence left dying in stage 4 cancer pain! It stopped the pain, vomiting & 2 metastatic tumors gone confirmed via MRI. I’m not claiming it cured it but feel it slowed it down and did kill two tumors. Marijuana/Opiates – WE SHOULD HAVE A CHOICE OR BOTH IF NEEDED! Shame on our Government for all the lies and trying to turn the people against one another. I hate the DEA, CDC, FDA! Just alone at what they allow in our food – the steroids, antibiotics it is sickening! They take away opiates yet cigarettes & alcohol are legal!?!?! What kind of [edit] is that! And marijuana has never caused one death – sch 1. The alcohol/cigarette related addictions/deaths as well as cases of cancer as other terminal illness they cause! Hell we need opiates for the pain from those illnesses from their legal substances they avoid talking about if I keep it real because they sure as hell wont!

Contrary to popular opinion, the external application is not the only way by which CBD oil can be consumed. By placing it under the tongue, many consume CBD oil directly. CBD oil has also been innovatively infused into products such as moisturizers and topical creams. CBD oil is an acceptable food supplement, serving as an addendum to cookies, brownies or even tacos! CBD oil capsules are a means by which they can be ingested.
The most commonly used form of CBD is CBD oil. Combining CBD extract with a carrier oil like coconut oil, it can be ingested or vaped, bringing a lot of variety. But because marijuana legalization is in such a murky situation with both federal and state laws to grapple with, CBD oil's legality can be hard to parse depending on where you are. Let's start with legality at the federal level.
By popular demand, we have also begun to carry several, high quality CBD pet products as well. For general purpose applications, we carry several, tasty tincture and oral spray options that are highly effective. Likewise, Pharma CBD capsules provide CBD purity via capsular ingestion. In addition, we have partnered with Therabis, the quality CBD maker of “Stop the Itch” and “Calm and Quiet”, the pet lovers’ ultimate go-to’s. Find these products by browsing our exclusive online inventory.
The 2014 Farm Bill[76] legalized the sale of "non-viable hemp material" grown within states participating in the Hemp Pilot Program.[77] This legislation defined hemp as cannabis containing less than 0.3% of THC delta-9, grown within the regulatory framework of the Hemp Pilot Program.[78] The 2018 Farm Bill allowed for interstate commerce of hemp derived products, though these products still fall under the purview of the FDA.[79][80]

The legal problems occur once the extracts contain higher percentages of THC, or when they’re made from cannabis plants that are no longer considered “hemp” (so basically high THC plants). Products with these extracts might be in violation of the United States Controlled Substances Act (US CSA). This is when laws regarding specific states or countries will apply.


In 2014, the Alabama state legislature passed SB 174, a restrictive cannabidiol (CBD) law. Officially entitled "Carly's Law," it offers an affirmative defense for the possession and use of CBD; however, the program is extremely limited and may not be able to provide CBD-rich medicine to patients in Alabama. In 2016, HB 61 was passed, which expanded the affirmative defense to several conditions and removed the requirement that patients must be enrolled in the UAB study program.
^ Nadulski T, Pragst F, Weinberg G, Roser P, Schnelle M, Fronk EM, Stadelmann AM (December 2005). "Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract". Ther Drug Monit. 27 (6): 799–810. doi:10.1097/01.ftd.0000177223.19294.5c. PMID 16306858.

Many a time, multiple cannabinoid compounds are used together, either knowingly or unknowingly.  It is, hence, tough to discern the extent to which each compound is involved in causing the desired effect. There are cases where a group of cannabinoids works synergistically in bringing about bodily reactions. Studies selectively employing CBD oil are few in number, but promising.


One classic use is in soaps. Hemp oil is also used in paints and lubricants, and as a body care product. It may be rubbed directly onto the skin to treat cracked, dry skin, or it can be blended into body oils, body creams, and other personal care products. Some people also use it as a dietary supplement, taking advantage of the high concentrations of essential fatty acids in unrefined hemp oil and using the oil as a dressing or garnish to improve nutrition.
One of the earliest success stories involves a young girl named Charlotte who was given an ingestible oil derived from Charlotte’s Web, a CBD strain that was specifically developed to provide her with all the benefits of the drug without the high. In less than two years, Charlotte went from a monthly seizure count of 1,200 to about three. Other success stories followed and more parents have begun to speak out, particularly parents who are desperate for access to this life-saving treatment.

Whatever the reason behind the confusion stirred up by Mr. Curtis Hill in the November of 2017, it seems we can finally put it in the back burner. People who were using this as a health regiment for various ailments (especially the epileptic ones) shall continue to use it as a remedy. It is because there is no need to worry about any law restricting it.
The key is to effectively gauge exactly how much CBD oil it takes to start managing your pain. If you start off right away with a maximum dose of a 600 mg tincture, you will have no idea how much of the product it actually took to treat your condition, and how much you wasted (this is also important because you do not want to exceed dosage and end up developing a tolerance to the active cannabinoids).
Dosage is important, because CBD can have side effects—the most common are tiredness, diarrhea, and changes in appetite and weight—so it’s best not to take more than you need. As CBD becomes more prevalent, says J. Michael Bostwick, M.D., a psychiatrist at Mayo Clinic in Rochester, MN, “I’m reasonably certain new kinds of side effects will emerge.”
Industrial hemp contains, by weight, far less CBD than CBD-rich cultivars such as Harlequin or Sour Tsunami. This means that producing a single 10 mL dose of CBD would require the cultivation and extraction of far more hemp than it would from whole-plant marijuana; thus raising the risk of exposing users to more contaminants. Hemp is classified as a “bioaccumulator,” or a plant that naturally absorbs toxicants from the soil.
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Down to its versatility and myriad of health benefits, Hemp Oil has reached an all time high in popularity, and men are women who want to make healthier lifestyle choices are reaching for the wellbeing product. Hemp is an all natural ingredient which can support your health and well-being through a high supply of minerals, antioxidants and amino acids. If you’re living in the UK its completely legal to find, purchase and consume this oil, it is however the availability and legality of hemp oil in the US is complex and confusing due to the the complex relationship between state and federal legislations.
CBD oil products can be somewhat expensive, which may be a barrier for individuals seeking treatment or relief from different conditions and disorders. cbdMD is a notable exception as far as price-point is concerned. cbdMD offers it’s premium, non-THC oils at a large variety of concentrations (300mg-5,000mg) as well as sizes (30mL and 60mL) . These oils are priced at $29.99 for 300mg oils and $99.99 for 1,500mg oils; these price-points are significantly below average.
Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.
Cannabis use has the hallmark pathologic features shared by all substance use disorders. Like other drugs of abuse, Cannabis causes compulsive drug-seeking behaviors, loss of self-control, withdrawal symptoms, and the propensity to relapse.57 Cannabis use disorder has been recognized as a bona fide disorder and has been included in the most recent version of the Diagnostic and Statistical Manual of Mental Disorders (fifth edition).58 Long-term clinical outcomes for Cannabis use disorder may be less severe than for other drugs of abuse but the addictive processes appears to be very similar. Animal models of addiction have clearly supported the notion that Cannabis has addictive properties.
This type of Hemp oil should not be confused with well known nutritional products that have been sold for some time now such as Hemp seed oil, which are sold for their high nutritional value and typically contain very little if any Cannabidiol or other Cannabinoids. These nutritional products are however, sold under the same laws that allow for Hemp based Cannabinoids to be sold legally.
Cannabis is by far the most widely cultivated, trafficked and abused illicit drug. Half of all drug seizures worldwide are cannabis seizures. The geographical spread of those seizures is also global, covering practically every country of the world. About 147 million people, 2.5% of the world population, consume cannabis (annual prevalence) compared with 0.2% consuming cocaine and 0.2% consuming opiates. In the present decade, cannabis abuse has grown more rapidly than cocaine and opiate abuse. The most rapid growth in cannabis abuse since the 1960s has been in developed countries in North America, Western Europe and Australia. Cannabis has become more closely linked to youth culture and the age of initiation is usually lower than for other drugs. An analysis of cannabis markets shows that low prices coincide with high levels of abuse, and vice versa. Cannabis appears to be price-inelastic in the short term, but fairly elastic over the longer term. Though the number of cannabis consumers is greater than opiate and cocaine consumers, the lower prices of cannabis mean that, in economic terms, the cannabis market is much smaller than the opiate or cocaine market.
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Years passed, and more studies rolled out with medically beneficial findings regarding cannabis until 2009 when Steep Hill Laboratory in Oakland, California, tested cannabis samples provided by Harborside Health Center to discover that a handful of cultivars contained more CBD than THC. This discovery kicked other labs into gear. They wanted to study medical cannabis to understand and potentially calibrate their cannabinoid ratios. Soon thereafter, laboratories uncovered CBD-dominant strains boasting 20:1 CBD to THC ratios, which opened up the cannabis market for a panoply of CBD products.
     In 2004, the 9th US Circuit Court of Appeals ruled that the naturally occurring Cannabinoids contained in non psychoactive varieties of Cannabis (industrial Hemp) are outside of the regulatory power of the DEA making hemp stalk and seed based cannabis oil legal after the DEA attempted to enforce a zero tolerance policy on the trace amounts of THC contained in Hemp products being sold at the time, such as nutritional Hemp seed oil. One can view these trace amount of THC being very similar to the trace amount of morphine and codeine found within poppy seeds used for baked goods.

Since 1929, Standard Process has been the visionary leader in whole food nutrient solutions. We apply systems thinking to holistic nutrition that empowers practitioners to transform lives. Dedicated to the whole food philosophy of our founder, Dr. Royal Lee, our goal is to carry on his mission to provide nutrients for the body that are as close as possible to how they are found in nature.
Despite the fact that Cannabis was grown on a large scale in many countries, the abuse as a narcotic remained uncommon in Western countries until relatively recently. People were largely unaware of the psychoactive properties of Cannabis and it is unlikely that early cultivars, selected mainly for their seed or fiber qualities, contained significant amounts of the psychoactive THC. The medicinal use of Cannabis was introduced in Europe only around 1840, by a young Irish doctor, William O’Shaughnessy, who served for the East India Trading Company in India, where the medicinal use of Cannabis was widespread. Unlike the European fiber Cannabis, these Indian varieties did contain a reasonable amount of bioactive cannabinoids. In the following decades, the medicinal use of Cannabis saw a short period of popularity both in Europe and in the United States. At the top of its popularity, more than 28 different medicinal preparations were available with Cannabis as active ingredient, which were recommended for indications as various as menstrual cramps, asthma, cough, insomnia, support of birth labor, migraine, throat infection, and withdrawal from opium use.27

Under the Controlled Substances Act – passed by Congress and enforced by the DEA – the mature stalk of a cannabis plant can be used legally (we will dive into this shortly) – which means CBD extracted from the stalk is also legal. Meanwhile, the 2014 Farm Bill allows states to pass laws relating to the extraction of CBD and other compounds from the hemp plant – specifically the industrial hemp plant – while also allowing industrial hemp to be legally imported from other countries. The FDA’s role in marijuana and CBD marketing and labeling has added additional complexity to the situation. Because many manufacturers attempt to market THC and CBD-containing products as dietary supplements, they violate the FD&C Act sections 201 (ff)(3)(B)(i) and (ii). Clinical investigations are currently needed to promote a product as a dietary supplement unless the supplement was publicly available before the Act was passed. The FDA, however, claims to believe in the validity of scientific research furthering the introduction of these substances for medical purposes and has approved the first CBD-containing epilepsy drug just this year. So…what’s the official word? Which details you should familiarize yourself with? Where should you start?
One of the most experienced practitioners in this field is Los Angeles physician Bonni Goldstein, who has used the compound to treat dozens of children with intractable epilepsy. She says about half of these patients have seen a significant drop in the number of seizures. “Used in the right way, with the right patient, CBD is extremely powerful,” she says. 

“The DEA makes it clear they don’t have to explicitly list anything as a controlled substance as long as a substance is intended for human ingestion, not approved as a drug by the (US Food and Drug Administration), or is structurally or pharmacologically similar to another controlled substance,” he told Leafly. “This DEA rulemaking change doesn’t make it any more illegal” than it previously was. The new rule “was an administrative change,” Armentano added. “It has nothing to do with law enforcement.”
In the United States, cannabis is overall the number four value crop, and is number one or two in many states including California, New York and Florida, averaging $3,000 per pound ($6,600/kg).[255][256] Some believe it generates an estimated $36 billion market.[257] Some have argued that this estimate is methodologically flawed, and makes unrealistic assumptions about the level of marijuana consumption. Other estimates claiming to correct for this flaw claim that the market is between $2.1-$4.3 billion.[248] The United Nations Office on Drugs and Crime claims in its 2008 World Drug Report that typical U.S. retail prices are $10–15 per gram (approximately $280–420 per ounce). Street prices in North America are known to range from about $40–$400 per ounce ($1.4–$14/g), depending on quality.[258]
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In a section devoted to CBD, or cannabidiol, analysts predict that the U.S. Food and Drug Administration will move to update its stance on the non-psychoactive ingredient found in cannabis and hemp that is widely held to have wellness properties. The recent U.S. 2019 Farm Bill fully legalized hemp for commercial use, but the FDA has retained a ban on adding CBD to food or drinks because it has not been fully researched. The agency has issued guidelines for the many companies eager to launch CBD-infused drinks and food products and has promised public talks on the matter, but for now companies are in a state of limbo.
^ Nadulski T, Pragst F, Weinberg G, Roser P, Schnelle M, Fronk EM, Stadelmann AM (December 2005). "Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract". Ther Drug Monit. 27 (6): 799–810. doi:10.1097/01.ftd.0000177223.19294.5c. PMID 16306858.
Elixinol has a wide range of products, but their CBD Tincture does the trick. It’s the cream of the crop regarding CBD oils and that reflects in its price. One dropper (1mg) from the 300 series contains 10mg of CBD. This allows you to get precise amounts of CBD and no guess work is required. Elixinol has received numerous awards for their products and extraction process.
As the PeaceHealth website suggests, hemp oil derives from a plant that contains high levels of the neurological chemical THC. This chemical can cause hallucinations, euphoria or high anxiety in supplement users when taken on a regular basis. As such, hemp oil supplements can cause similar effects in some patients using the herb for the treatment of any disorder. It is recommended that supplement users not take hemp oil products prior to operating machinery or driving due to the risk of these hallucinogenic properties. This is especially true to individuals who are overly-sensitive to THC, which can be determined by visiting your medical doctor for more information.
Truth be told, one of the biggest draws to using CBD oil for pain has been the fact that it has little distinguishable side-effects or contraindications with other medications. In fact, in a massive report that was published by the World Health Organization during last year’s 2017 Expert Committee on Drug Dependence, it was (finally) declared to the world that CBD is a “safe, well tolerated [compound, which] is not associated with any significant adverse public health effects.”

New companies are already popping up, making products from Whole Plant extracts taken from high quality domestic or European Hemp plants with more complete Cannabinoid profiles and offering concentrations of CBD in their extracts similar to what is obtainable from strains such as Charlotte's Web. Charlotte's Web itself has recently been reclassified from Marijuana by the state of CO as a Hemp variety (story here) which will allow for the sales of Hemp based finishing products derived from it in all U.S. states, the same as other legal Hemp based CBD nutritional supplements that are currently being sold.
Whatever the reason behind the confusion stirred up by Mr. Curtis Hill in the November of 2017, it seems we can finally put it in the back burner. People who were using this as a health regiment for various ailments (especially the epileptic ones) shall continue to use it as a remedy. It is because there is no need to worry about any law restricting it.
Cannabis flavonoids in whole cannabis extracts may also contribute useful activity (McPartland and Russo 2001). Apigenin inhibits TNF-α (Gerritsen et al 1995), a mechanism germane to multiple sclerosis and rheumatoid arthritis. Cannflavin A, a flavone unique to cannabis, inhibits PGE-2 thirty times more potently than aspirin (Barrett et al 1986), but has not been subsequently investigated.
CBD is a 5-HT1A receptor agonist, which may also contribute to an anxiolytic effect.[155] This likely means the high concentrations of CBD found in Cannabis indica mitigate the anxiogenic effect of THC significantly.[155] The cannabis industry claims that sativa strains provide a more stimulating psychoactive high while indica strains are more sedating with a body high.[156] However this is disputed by researchers.[157]

Medical marijuana in the U.S. is controlled at the state level. Per federal law, cannabis is illegal as noted in the Controlled Substances Act, but the federal government has stated they will not actively prosecute patients and caregivers complying with state medical marijuana laws. However, use of medical marijuana outside of the state laws for illegal use or trafficking will not be tolerated by state or federal government.

Another concern is about medications with which CBD might interact. This won’t be an issue with most drugs, says Sunil Kumar Aggarwal, M.D., Ph.D., a palliative medicine physician and scientist who studies cannabis and integrates it into his Seattle medical practice. The exceptions are blood thinners, IV antibiotics, and other drugs whose exact dosing is crucial and must be monitored closely, he says. (Of course, if you have a health problem, talk to your doctor before using CBD, and never take it instead of seeing your physician for a serious condition.)
At sufficient doses (400-600 mg), CBD can alleviate situational anxiety, such as public speaking. Interestingly, cannabis cultivars, or strains, that are high in CBD and low in THC are better than other cultivars for alleviating depression. But when used over a long period of time, any kind of cannabis could make depression worse.  Although clinical trials in people haven’t yet been completed, there is very compelling “petri dish” evidence that CBD can reduce inflammation, for painful conditions such as Crohn’s disease, and fight some cancerous tumors. There is a massive amount of scientific research being done on CBD right now, and we are likely to see many medical breakthroughs in the next decade.
Because it takes a significantly larger amount of hemp stalks to produce hemp oil, there is an increased risk of contamination of toxins contained within the plant. This is a result of hemp's strong bio-accumulator properties, where it pulls toxins from the soil it grows in. Many hemp oils are also known to lack the full spectrum of terpenes and other cannabinoids that are believed to act synergistically with the CBD, meaning that consumers receive less of a benefit. That being said, there are some brands that test rigorously to make sure that the CBD content, as well as the terpenes and other cannabinoids, are up to par. It's a good sign if they offer to provide a certificate of analysis, which will tell you what kind of compounds are in the hemp oil and in what concentrations
This is exciting for many, but also complicated due to the fact that possession of marijuana is still considered a criminal offense at the federal level. Transporting marijuana across state lines, drug tests for employees following a visit to one of the states where marijuana is legal, and other complications have led many to avoid the topic – and consumption – altogether.
Before thing’s started getting out of hand with chronic pain really settling in, I used CBD oil for about a year. I kept waiting and waiting to feel better. Until I just couldn’t take the pain any longer. Than I tried Herion. I did not like that at all, pluse was a little frightened of it. Than I finally asked for pain meds. I just had to find the right dosage. Was doing very good with it. Than I was cut cut back to guidelines, now not so good again. So now what? Their he’ll bent on making Kratom illegals. They just want us all to suffer and die, I’m convinced.
Ironically, the only four states where you can be absolutely sure that the CBD content claimed on the label is the CBD content in the bottle are Colorado, Washington, Oregon, and Alaska, where adult-use cannabis is legal and regulated. That’s because the CBD products available in licensed retail cannabis stores must pass state-mandated lab tests to assure their purity and potency. In fact, if these products haven’t gone through state testing, they’re liable to be seized, as happened recently in Alaska.
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But he wasn’t finished. In February of 1980, Dr. Mechoulam teamed up with South American researchers to publish a study regarding cannabis and epilepsy. This study is seen as one of the earliest double-blind studies of CBD on clinical subjects. The study Dr. Mechoulam and his team conducted included 16 people, many of whom were children, who all suffered from severe epilepsy. The results were startling: Every subject who received CBD experienced improvement in their condition with little to no side effects. This anticonvulsant study has since proven to be an integral milestone in the world of clinical marijuana research, but largely went unnoticed at the time.
Ringo’s Gift: This cultivar is named after the cannabidiol pioneer, Lawrence Ringo. Ringo’s Gift is a cross between two other CBD-rich strains, AC/DC and Harle-tsu. Its CBD to THC ratio varies from 1:1 to 22:1, but it consistently favors CBD. Ringo’s Gift smells of earthy pine and promises full-bodied relaxation in tandem with calming cerebral effects which, together, silence pain and anxiety.
Almost everything we use in our diet to prevent or manage health problems has some risk of side effects, and hemp oil is no exception. Firstly it is important to note, however, that negative side effects of hemp oil are rare and some only occur in extreme cases, they can also be considered minor in comparison to the side effect of pharmaceuticals. To date, there have been no reported cases of toxicity from the ingestion of hemp seed oil.
CBD oil alleviates physical pain and anxiety – both of which can have a negative impact on sleep. Additionally, CBD oil can actually prolong sleep for some, leading to more rest from night to night. Most medical experts agree that marijuana is not particularly beneficial for individuals with medical conditions and/or mental health disorders, as the THC can increase their symptoms; this makes CBD oil a good alternative option for people with the following sleep disorders and medical conditions.

It is main ingredient of the product which plays an important role in the functioning of CBD Balm. Cannabidiol or CBD is the main component in the balm and this is an important component of cannabis plant. CBD is non-psychoactive and like its other counterpart THC, this component does not produce a ‘high’. There are many medical benefits of CBD and this is the reason that it has been legalized in almost 50 states in the US. Medical cannabis works on the endocannabinoid system in the body. It helps in assisting and regulating various kinds of functions including response to inflammation, relaxation, appetite, cognitive function of the brain etc.
Marijuana-derived CBD products, on the other hand, don’t enjoy the same luxuries. Because it has been derived from THC-rich marijuana, marijuana-derived CBD, even its isolated from, is considered as a byproduct of marijuana and is judged accordingly. In some states, marijuana-derived CBD is completely legal, while in others, it is completely illegal, but in most states, its a bit of a mixed bag, each state having CBD-specific laws.
In the 1950s, the Narcotics Control Act and the Boggs Act stiffened penalties for marijuana possession, with first-time offenses requiring two to 10 year sentences and a minimum $20,000 fine, according to PBS.org. Penalties were relaxed in the 1970s, but President Ronald Reagan increased federal penalties for marijuana possession in the 1980s. On the federal level, marijuana is now regulated under the Controlled Substances Act as a schedule 1 drug, meaning the government considers it to have a high potential for abuse with no legitimate medical or therapeutic uses.
^ Crean RD, Crane NA, Mason BJ (March 2011). "An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions". Journal of Addiction Medicine. 5 (1): 1–8. doi:10.1097/ADM.0b013e31820c23fa. PMC 3037578. PMID 21321675. Cannabis appears to continue to exert impairing effects in executive functions even after 3 weeks of abstinence and beyond. While basic attentional and working memory abilities are largely restored, the most enduring and detectable deficits are seen in decision-making, concept formation and planning.

As of 2019, there are only three states with restrictions on all cannabis and cannabis-derived products. These are Idaho, Nebraska, and South Dakota. Even though hemp is likely to become more accessible in these territories soon, if you are in one of these states, it is crucial that you know what kind of CBD extract you are using and where it comes from.
The list of states where medical or recreational use of marijuana and CBD is legal keeps growing. Thirty-three states and Washington, D.C., have passed medical marijuana laws (including 10 states and the nation's capital where recreational and medical use is legal), says Paul Armentano, deputy director of the National Organization for the Reform of Marijuana Laws (NORML). Also, 14 states have enacted CBD-explicit medical laws.

CBD e-liquids are made for vaporizers or electronic cigarettes. Usually, hemp extract or pure CBD is mixed with a classic e-liquid base called PG/VG. The e-liquids are then inserted into a cartridge or atomizer for an electronic cigarette. You may see the CBD vape oil used interchangeably with CBD e-liquids, so keep that in mind and don’t vape your regular CBD-rich oil unless you want a not so enjoyable experience. 

CBD, or cannabidiol, is a cannabinoid found in the hemp plant. As we’ve discovered more about the human species as well as the plants that we’ve learned of the immense health value that CBD brings to the table. It has quickly become a staple supplement for millions who seek a natural alternative to dangerous pharmaceuticals, alien to nature’s perfect remedies.


Does anybody know about cbd vs thc for chronic exhaustion? There are times that I can barely get out of bed and can’t do work due to it, and it has gotten my mood swings to go over the roof! I don’t have much interest in doing just thc because it makes me feel more lethargic, but cbd has seem to be able to help me! I need to know if someone has used it for this problem, and is results


Physiological manifestations like stress, and poor diet may negatively impact other systems in the body via specific cellular processes. Nutrition plays an important role in preserving various systemic and metabolic functions by supplying the appropriate dietary needs to the body system. The nutrient signaling pathways are coupled to cellular processes, and the cross-talk between the two is critical in maintaining a well-balanced systemic function of the body. The systemic imbalance may occur under circumstances such as stress, and fatigue, which may trigger inflammatory responses in the body3 and inflammation may cause unwanted health conditions. It has been shown that various dietary components may support key resolution pathways to inflammation, energy balance and metabolism via the ECS.4,5,6,7,8 Nutrients that may support healthy inflammatory response include omega-3 fatty acids, and antioxidants, from a whole food matrix in the form of phytonutrients.2,9
All CBD products start out the same way: as an extract from the leaves and flowers of cannabis plants. At Green Roads, we only extract CBD from hemp, defined as any variety of cannabis plant containing less than 0.3% THC by dry weight. Cannabinoids and terpenes are produced by tiny glands on the leaves and flowers of cannabis plants known as trichomes. The compounds produced by these trichomes give cannabis both its rich aroma and its nutraceutical effects.
In a study with HIV-positive adult men, blood concentrations of ghrelin and other appetitive hormones (leptin, PYY, and insulin) were tested after having received smoked medicinal cannabis or matched placebo for HIV-associated neuropathic pain. Cannabis administration, as compared to placebo, significantly increased ghrelin concentrations in this study. In addition, leptin and PYY levels were, respectively, increased and decreased, but no impact on insulin levels was found (Riggs et al., 2012).
Marijuana or marihuana (herbal cannabis),[166] consists of the dried flowers and subtending leaves and stems of the female Cannabis plant.[167][168][169][170] This is the most widely consumed form,[170] containing 3% to 20% THC,[171] with reports of up-to 33% THC.[172] This is the stock material from which all other preparations are derived. Although herbal cannabis and industrial hemp derive from the same species and contain the psychoactive component (THC), they are distinct strains with unique biochemical compositions and uses. Hemp has lower concentrations of THC and higher concentrations of CBD, which decreases the psychoactive effects[173][174]

Distinguishing cannabis and hemp can be confusing, so let's make it simple. There are many varietals of Cannabis sativa, all of which have different amounts of THC and CBD. Cannabis sativa varietals that have more than 0.3 percent THC are commonly referred to as marijuana. Hemp is any varietal of Cannabis sativa that contains less than 0.3 percent THC.
Chronic pain can be a very devastating diagnosis. For those of us without this condition, it’s hard to imagine what someone with chronic pain is going through. Chronic pain is usually secondary to some form of trauma, making a bad situation far worse. Imagine the worst pain you have every experienced and then try to imagine having that pain day in and day out for months or worse, for years.
You can use Nutiva Organic Hempseed Oil in smoothies, salads, vegetables and pasta dishes. To conserve the essential fatty acids, we suggest you use it raw or gently heated. It's not suitable for frying. Hemp is loaded with all 20 amino acids, including the nine essential amino acids that are not manufactured in the body, and must come from food. Amino acids are essential for many metabolic processes, including building muscle tissue.
Zammit and colleagues’ findings were supported in a 3-year longitudinal study of the relationship between self-reported cannabis use and psychosis in a community sample of 4848 people in the Netherlands (van Os et al., 2002). Van Os and colleagues reported that cannabis use at baseline predicted an increased risk of psychotic symptoms during the follow-up period in individuals who had not reported psychiatric symptoms at baseline. There was a dose–response relationship between frequency of cannabis use at baseline and risk of psychotic symptoms during the follow-up period. These relationships persisted when they statistically controlled for the effects of other drug use. The relationship between cannabis use and psychotic symptoms was also stronger for cases with more severe psychotic symptoms.

Hemp being federally legal would be huge for the CBD industry, as CBD oil made from hemp extract (a plant that has very low amounts of THC) would be legal. A new, more available form of CBD would also allow for more research on the subject of cannabidiol, and perhaps the entire marijuana plant. More research brings the potential of coming closer to full legalization.
Quality is a particular concern, because cannabis plants easily soak up heavy metals from pesticides and other contaminants, Marcu says. If you are buying online, look for a company that documents how it tests its products. (If the website doesn’t indicate this, call and ask.) “Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
Republican Governor Eric Holcomb, with the help of Republican dominant General Assembly, passed the law on Wednesday. He signed into law Senate Enrolled Act 52 that explicitly legalizes CBD oil. This was done in response to the opinion set by Attorney General Curtis Hill. The opinion that essentially said that “Simply put, cannabidiol is a Schedule 1 controlled substance because marijuana is a Schedule 1 controlled substance,”
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